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Hazard Xn: Harmful;
Risk R20/21/22
Safety
Human poison by ingestion. Experimental poison by ingestion, skin contact, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of F− and NOx. See also FLUORIDES.
Hazard Codes:
Xn
Risk Statements:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: YP2660000
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LDLo | subcutaneous | 8mg/kg (8mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936. | |
| man | LDLo | oral | 143mg/kg (143mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936. | |
| mouse | LDLo | oral | 14mg/kg (14mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936. | |
| mouse | LDLo | skin | 18mg/kg (18mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936. | |
| mouse | LDLo | subcutaneous | 11mg/kg (11mg/kg) | behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936. |
| rat | LDLo | subcutaneous | 12mg/kg (12mg/kg) | behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold behavioral: irritability | Journal of Pharmacology and Experimental Therapeutics. Vol. 73, Pg. 176, 1941. |
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