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Tyrosine, 3-fluoro- cas no:139-26-4

Synonyms: DL-Tyrosine,3-fluoro-; Tyrosine, 3-fluoro-, DL- (8CI); 3-Fluoro-DL-tyrosine;3-Fluorotyrosine; Ba 2745; DL-3-Fluorotyrosin; DL-3-Fluorotyrosine;DL-m-Fluorotyrosine; Fluorthyrin; NSC 83231; Pardinon; m-Fluoro-DL-tyrosine

Identification
NameTyrosine, 3-fluoro-
CAS139-26-4
SynonymsDL-Tyrosine,3-fluoro-; Tyrosine, 3-fluoro-, DL- (8CI); 3-Fluoro-DL-tyrosine;3-Fluorotyrosine; Ba 2745; DL-3-Fluorotyrosin; DL-3-Fluorotyrosine;DL-m-Fluorotyrosine; Fluorthyrin; NSC 83231; Pardinon; m-Fluoro-DL-tyrosine
EINECS(EC#)206-964-0
Molecular FormulaC9H10 F N O3
Molecular Weight199.20
Chemical Properties
refractive index1.563
storage temp2-8°C
Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Human poison by ingestion. Experimental poison by ingestion, skin contact, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of F and NOx. See also FLUORIDES. 
Hazard Codes:
HarmfulXn
Risk Statements:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: YP2660000


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 8mg/kg (8mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
man LDLo oral 143mg/kg (143mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
mouse LDLo oral 14mg/kg (14mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
mouse LDLo skin 18mg/kg (18mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
mouse LDLo subcutaneous 11mg/kg (11mg/kg) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
rat LDLo subcutaneous 12mg/kg (12mg/kg) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold behavioral: irritability Journal of Pharmacology and Experimental Therapeutics. Vol. 73, Pg. 176, 1941.

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