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Ethyl acrylate cas no:140-88-5

Synonyms: Acrylic acid ethyl ester; EA

Identification
NameEthyl acrylate
CAS140-88-5
SynonymsAcrylic acid ethyl ester; EA
EINECS(EC#)205-438-8
Molecular FormulaC5H8O2
Molecular Weight100.12
Chemical Properties
Appearancecolourless liquid
refractive index1.405-1.407
storage tempRefrigerator
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Hazard F:Flammable
Risk R11;R20/21/22;R36/37/38;R43
Safety

Hazard Codes of Ethyl acrylate (CAS NO.140-88-5):?FlammableF,HarmfulXn
Risk Statements: 11-20/21/22-36/37/38-43?
R11:Highly flammable.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R43: May cause sensitization by skin contact.
Safety Statements: 9-16-33-36/37?
S9: Keep container in a well-ventilated place.?
S16: Keep away from sources of ignition.?
S33: Take precautionary measures against static discharges.?
S36/37: Wear suitable protective clothing and gloves.
RIDADR: UN 1917 3/PG 2
WGK Germany: 2
RTECS: AT0700000
F: 8
HazardClass: 3
PackingGroup: II


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD oral > 800uL/kg (0.8mL/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING
National Technical Information Service. Vol. OTS0521003,
guinea pig LCLo inhalation 1204ppm/7H (1204ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: COUGH

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 317, 1949.
human TCLo inhalation 50ppm (50ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 75, 1969.
monkey LC inhalation > 75ppm/6H (75ppm) SENSE ORGANS AND SPECIAL SENSES: DEVIATED NASAL SEPTUM: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: ULCERATED NASAL SEPTUM: OLFACTION
Toxicologist. Vol. 36(1, Pg. pt2), 113.
mouse LC50 inhalation 16200mg/m3 (16200mg/m3) ? Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(9), Pg. 55, 1979.
mouse LD50 intraperitoneal 599mg/kg (599mg/kg) ? Journal of Dental Research. Vol. 51, Pg. 526, 1972.
mouse LD50 oral 1799mg/kg (1799mg/kg) ? Toxicology Letters. Vol. 11, Pg. 125, 1982.
mouse LD50 skin 2997mg/kg (2997mg/kg) ? National Technical Information Service. Vol. OTS0520999,
rabbit LCLo inhalation 1204ppm/7H (1204ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 317, 1949.
rabbit LD50 oral 370mg/kg (370mg/kg) GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION National Technical Information Service. Vol. OTS0521003,
rabbit LD50 skin 500uL/kg (0.5mL/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LIVER: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
National Technical Information Service. Vol. OTS0520180,
rat LC50 inhalation 1414ppm/4H (1414ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
National Technical Information Service. Vol. OTS0520180,
rat LD50 intraperitoneal 450mg/kg (450mg/kg) ? Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 36, Pg. 58, 1975.
rat LD50 oral 800mg/kg (800mg/kg) ? Bromatologia i Chemia Toksykologiczna. Vol. 12, Pg. 405, 1979.
rat LDLo skin 1800mg/kg (1800mg/kg) ? Polish Journal of Pharmacology and Pharmacy. Vol. 32, Pg. 223, 1980.

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