| human |
TDLo |
intramuscular |
3mg/kg/D (3mg/kg) |
peripheral nerve and sensation: paresthesis behavioral: ataxia |
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 488, 1969. |
| human |
TDLo |
oral |
8570mg/kg (8570mg/kg) |
gastrointestinal: "hypermotility, diarrhea" gastrointestinal: nausea or vomiting
|
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 488, 1969. |
| mouse |
LD50 |
intramuscular |
61400ug/kg (61.4mg/kg) |
behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: other changes behavioral: convulsions or effect on seizure threshold
|
Antibiotiki. Vol. 21, Pg. 846, 1976. |
| mouse |
LD50 |
intravenous |
3980ug/kg (3.98mg/kg) |
behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: other changes
|
Antibiotiki. Vol. 21, Pg. 846, 1976. |
| mouse |
LDLo |
intraperitoneal |
13mg/kg (13mg/kg) |
behavioral: convulsions or effect on seizure threshold behavioral: muscle weakness lungs, thorax, or respiration: other changes
|
Lancet. Vol. 254, Pg. 127, 1948. |
| rat |
LD50 |
intramuscular |
13300ug/kg (13.3mg/kg) |
behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: other changes behavioral: convulsions or effect on seizure threshold
|
Antibiotiki. Vol. 21, Pg. 846, 1976. |
| rat |
LD50 |
subcutaneous |
50mg/kg (50mg/kg) |
vascular: regional or general arteriolar or venous dilation |
British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 215, 1955. |
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