Polymyxin B sulfate cas no:1405-20-5
Synonyms: Campho-Phenique Antibiotic Plus Pain Relief Ointment;Ophthocort;Neosporin Plus;Dexacidin;Neobacimyx (Veterinary);Polymixin B sulfate (JP14);Aerosporin (TN);Poly-Pred;Drotic;Pediotic Suspension;Statrol;2-[(4-amino-2-formamido-butanoyl)amino]-N-[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]-4-hydroxy-butanamide; sulfuric acid;Neosporin;Aerosporin;Chloromyxin;Otocort;Mastimyxin;
NamePolymyxin B sulfate
CAS1405-20-5
SynonymsCampho-Phenique Antibiotic Plus Pain Relief Ointment;Ophthocort;Neosporin Plus;Dexacidin;Neobacimyx (Veterinary);Polymixin B sulfate (JP14);Aerosporin (TN);Poly-Pred;Drotic;Pediotic Suspension;Statrol;2-[(4-amino-2-formamido-butanoyl)amino]-N-[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]-4-hydroxy-butanamide; sulfuric acid;Neosporin;Aerosporin;Chloromyxin;Otocort;Mastimyxin;
EINECS(EC#)215-774-7
Molecular FormulaC56H98N16O13.H2SO4
Molecular Weight1301.56
AppearanceWhite crystalline powder
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn: Harmful;
Risk R22
Safety
Poison by intravenous, subcutaneous, intraperitoneal and intracerebral routes. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also POLYMYXIN B.
Hazard Codes:?
Xn
Risk Statements: 22?
R22:Harmful if swallowed.
Safety Statements: 22-24/25?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.
| 1. |
??? |
dnd-esc 50?mg/L
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MUREAV ?? Mutation Research. 89 (1981),95. |
| 2. |
??? |
orl-mus LD50:790?mg/kg
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NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794. |
| 3. |
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ipr-mus LD50:20,500?μg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794. |
| 4. |
??? |
scu-mus LD50:59,500?μg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794. |
| 5. |
??? |
ivn-mus LD50:5400?μg/kg
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??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794. |
| 6. |
??? |
ivn-dog LDLo:8?mg/kg
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??? |
INURAQ ?? Investigative Urology. 6 (1969),505. |
| 7. |
??? |
ice-dog LDLo:320?μg/kg
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??? |
BJPCAL ?? British Journal of Pharmacology and Chemotherapy. 23 (1964),552. |
