1405-20-5|Polymyxin B sulfateProducts Supply - Chemical intermediates Network

Polymyxin B sulfate cas no:1405-20-5

Synonyms: Campho-Phenique Antibiotic Plus Pain Relief Ointment;Ophthocort;Neosporin Plus;Dexacidin;Neobacimyx (Veterinary);Polymixin B sulfate (JP14);Aerosporin (TN);Poly-Pred;Drotic;Pediotic Suspension;Statrol;2-[(4-amino-2-formamido-butanoyl)amino]-N-[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]-4-hydroxy-butanamide; sulfuric acid;Neosporin;Aerosporin;Chloromyxin;Otocort;Mastimyxin;

Identification

NamePolymyxin B sulfate
CAS1405-20-5
SynonymsCampho-Phenique Antibiotic Plus Pain Relief Ointment;Ophthocort;Neosporin Plus;Dexacidin;Neobacimyx (Veterinary);Polymixin B sulfate (JP14);Aerosporin (TN);Poly-Pred;Drotic;Pediotic Suspension;Statrol;2-[(4-amino-2-formamido-butanoyl)amino]-N-[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]-4-hydroxy-butanamide; sulfuric acid;Neosporin;Aerosporin;Chloromyxin;Otocort;Mastimyxin;
EINECS(EC#)215-774-7
Molecular FormulaC₅₆H₉₈N₁₆O₁₃^.H₂SO₄
Molecular Weight1301.56

Chemical Properties

AppearanceWhite crystalline powder
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Poison by intravenous, subcutaneous, intraperitoneal and intracerebral routes. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO_x and NO_x. See also POLYMYXIN B.
Hazard Codes:? Harmful Xn
Risk Statements: 22?
R22:Harmful if swallowed.
Safety Statements: 22-24/25?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.

Toxicity

1.	???	dnd-esc 50?mg/L	???	MUREAV ?? Mutation Research. 89 (1981),95.
2.	???	orl-mus LD50:790?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794.
3.	???	ipr-mus LD50:20,500?μg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794.
4.	???	scu-mus LD50:59,500?μg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794.
5.	???	ivn-mus LD50:5400?μg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),794.
6.	???	ivn-dog LDLo:8?mg/kg	???	INURAQ ?? Investigative Urology. 6 (1969),505.
7.	???	ice-dog LDLo:320?μg/kg	???	BJPCAL ?? British Journal of Pharmacology and Chemotherapy. 23 (1964),552.

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Ningbo Distant Chemicals Co.,Ltd: Tel:; Address: 14-04,NO 668,Jingjia road,Jiangdong district,Ningbo,China

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Changzhou Institute of Materia Medica: Tel:+86-(519)-8881-0897; Address: No.300,Yanling Middle Road, Changzhou, Jiangsu 213003,

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Nanjing Samwon International Limited: Tel:+86-(25)-84873444; Address: 1108, BLDG B, New Century Plaza, No 1, South Taiping Rd., Nanjing, Jiangsu 210002,

Polymyxin B sulfate cas no:1405-20-5

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