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Ethyl acetate cas no:141-78-6

Synonyms: Acetic acid ethyl ester; ethyl acetate B&J brand 4 L; ETHYLACETATE ULTRA RESI-ANAL.; ETHYL ACETATE CAPILLARY GRADE; Ethyl Acetate Specially Purified - SPECIFIED; Acetic Ether; RFE; acetic ester

Identification
NameEthyl acetate
CAS141-78-6
SynonymsAcetic acid ethyl ester; ethyl acetate B&J brand 4 L; ETHYLACETATE ULTRA RESI-ANAL.; ETHYL ACETATE CAPILLARY GRADE; Ethyl Acetate Specially Purified - SPECIFIED; Acetic Ether; RFE; acetic ester
EINECS(EC#)205-500-4
Molecular FormulaC4H8O2
Molecular Weight88.1
Chemical Properties
AppearanceColorless liquid
refractive index1.371-1.374
Safety Data

Hazard F:Flammable
Risk R11;R36;R66;R67
Safety

Hazard Codes:?FlammableF,?IrritantXi,HarmfulXn, ToxicT
Risk Statements:?11-36-66-67-20/21/22-10-39-23/24/25-68
11:?Highly Flammable?
36: Irritating to the eyes?
66:?Repeated exposure may cause skin dryness or cracking?
67:?Vapors may cause drowsiness and dizziness
20/21/22: Harmful by inhalation, in contact with skin and if swallowed?
10:?Flammable??
39: Danger of very serious irreversible effects.
23/24/25:?Toxic by inhalation, in contact with skin and if swallowed??
68: Possible risk of irreversible effects.
Safety Statements:? 16-26-33-36/37-45-7-25
16: Keep away from sources of ignition - No smoking?
26:?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
33:?Take precautionary measures against static discharges?
36/37:?Wear suitable protective clothing and gloves?
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
7: Keep container tightly closed?
25: Avoid contact with eyes
RIDADR:?UN 1173 3/PG 2
WGK Germany: 1
F:?1: Sensitive to air and humidity.
HazardClass:?3
PackingGroup:?II


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 61gm/m3 (61000mg/m3) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 336, 1955.
cat LD50 subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: OTHER CHANGES
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
guinea pig LD50 oral 5500mg/kg (5500mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: COMA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(4), Pg. 66, 1983.
guinea pig LD50 subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
human TCLo inhalation 400ppm (400ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mouse LC50 inhalation 45gm/m3/2H (45000mg/m3) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 65, 1982.
mouse LD50 intraperitoneal 709mg/kg (709mg/kg) ? Shell Chemical Company. Unpublished Report. Vol. -, Pg. 5, 1961.
mouse LD50 oral 4100mg/kg (4100mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: COMA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(4), Pg. 66, 1983.
rabbit LD50 oral 4935mg/kg (4935mg/kg) ? Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
rabbit LD50 skin > 20mL/kg (20mL/kg) ? Union Carbide Data Sheet. Vol. 10/4/1968,
rat LC50 inhalation 200gm/m3 (200000mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.
rat LD50 oral 5620mg/kg (5620mg/kg) ? Yakkyoku. Pharmacy. Vol. 32, Pg. 1241, 1981.
rat LDLo subcutaneous 5gm/kg (5000mg/kg) ? Bolletino della Societe Italiana di Biologia Sperimentale. Vol. 18, Pg. 45, 1943.

supplier list

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