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Propanedioic acid,sodium salt (1:2) cas no:141-95-7

Synonyms: Malonicacid, disodium salt (8CI);Propanedioic acid, disodium salt (9CI);Disodiummalonate;Sodium malonate;

Identification
NamePropanedioic acid,sodium salt (1:2)
CAS141-95-7
SynonymsMalonicacid, disodium salt (8CI);Propanedioic acid, disodium salt (9CI);Disodiummalonate;Sodium malonate;
EINECS(EC#)205-514-0
Molecular FormulaC3H2Na2O4
Molecular Weight104.06146
Chemical Properties
Appearancewhite crystalline powder
Safety Data

Safety

Safety Statements:  22-24/25
22: Sodium malonate (141-95-7) is harmful if swallowed
24/25:  Toxic in contact with skin and if swallowed
WGK Germany:  3
RTECS:  OO1750000


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1550mg/kg (1550mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 79, Pg. 461, 1949.
mouse LD50 intravenous 2100mg/kg (2100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

CARDIAC: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 79, Pg. 461, 1949.
rabbit LD50 intravenous 660mg/kg (660mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 79, Pg. 461, 1949.
rabbit LDLo subcutaneous 1584mg/kg (1584mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

ENDOCRINE: HYPERGLYCEMIA
Journal of Biological Chemistry. Vol. 161, Pg. 55, 1945.
rat LD50 intraperitoneal 1100mg/kg (1100mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 17, Pg. 814, 1965.

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