Nisin cas no:1414-45-5
Synonyms: 1-Thia-4,7,10,13,16,19-hexaazacyclodocosane, cyclic peptide deriv.;1H,9H-Pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecine, cyclic peptide deriv.;9,19-Dithia-2,5,13,16,22-pentaazabicyclo[9.9.2]docosane, cyclic peptide deriv.;Ambicin N;Delvoplus;MicroGARD MG 300;Nisaplin;Nisin(1-34);Nisitrol;Novasin;NisinA (9CI);
NameNisin
CAS1414-45-5
Synonyms1-Thia-4,7,10,13,16,19-hexaazacyclodocosane, cyclic peptide deriv.;1H,9H-Pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecine, cyclic peptide deriv.;9,19-Dithia-2,5,13,16,22-pentaazabicyclo[9.9.2]docosane, cyclic peptide deriv.;Ambicin N;Delvoplus;MicroGARD MG 300;Nisaplin;Nisin(1-34);Nisitrol;Novasin;NisinA (9CI);
EINECS(EC#)215-807-5
Molecular FormulaC143H230N42O37S7
Molecular Weight3354.08
Appearancegrey or white or light yellow powder
refractive index1.635
storage temp2-8°C
Hazard Xn: Harmful;
Risk R22
Safety
When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:?
Xn
Risk Statements: 22-36/37/38
?R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS of Nisin (CAS NO.1414-45-5): QU3340000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intravenous |
100mg/kg (100mg/kg) |
? |
"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(2), Pg. 228, 1980. |
| rabbit |
LDLo |
parenteral |
2250ug/kg (2.25mg/kg) |
BRAIN AND COVERINGS: MENINGEAL CHANGES
BRAIN AND COVERINGS: CHANGES IN CEREBRAL SPINAL FLUID
BEHAVIORAL: IRRITABILITY |
British Journal of Pharmacology and Chemotherapy. Vol. 7, Pg. 438, 1952. |
