CODEINE SULFATE cas no:1420-53-7

NameCODEINE SULFATE
CAS1420-53-7
SynonymsCODEINE SULFATE;CODEINE SULPHATE;DICODEINE SULFATE;3-METHYLMORPHINE SULFATE SALT;CODEINE SULFATE OPIATE ANALGESIC, ANT;Codeine sulfate salt
EINECS(EC#)215-818-5
Molecular FormulaC₃₆H₄₂N₂O₆ . O₄S
Molecular Weight694.86

Hazard Xn: Harmful;
Risk 22
Safety

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. An addictive, narcotic drug. When Codeine sulfate (CAS NO.1420-53-7) is heated to decomposition it emits very toxic fumes of NO_x and SO_x. See also CODEINE.

Hazard Codes Xn
Risk Statements 22
R22: Codeine sulfate (CAS NO.1420-53-7) is harmful if swallowed.
RTECS QD1400000

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	143mg/kg (143mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmaceutical Sciences. Vol. 63, Pg. 451, 1974.
mouse	LD50	intravenous	68mg/kg (68mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961.
mouse	LD50	oral	395mg/kg (395mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961.
mouse	LD50	subcutaneous	183mg/kg (183mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961.
rat	LD50	intraperitoneal	107mg/kg (107mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT BEHAVIORAL: REGIDITY	Toxicology. Vol. 14, Pg. 217, 1979.
rat	LD50	intravenous	55mg/kg (55mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961.
rat	LD50	oral	430mg/kg (430mg/kg)	BEHAVIORAL: ANALGESIA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 123, Pg. 48, 1959.
rat	LD50	subcutaneous	332mg/kg (332mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 332, 1961.