Benzeneacetic acid,4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester cas no:1421-14-3

NameBenzeneacetic acid,4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester
CAS1421-14-3
SynonymsAceticacid, [4-[(diethylcarbamoyl)methoxy]-3-methoxyphenyl]-, propyl ester (7CI,8CI);13245RP; 2180TH; BAY 1420; Epontol; FBA 1420; Fabantol; Fabontal; Propanidid;Propanidide; Propantan; Propyl4-(N,N-diethylcarbamidomethoxy)-3-methoxy-phenylacetate; Propyl[4-[(diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetate; Sombrevin; TH 2180; WH5668; [4-[(Diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetic acid propyl ester
EINECS(EC#)215-822-7
Molecular FormulaC18H27 N O5
Molecular Weight337.46

refractive index1.503

Safety

Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human systemic effects by intravenous route: general anesthesia. When Propanidide (CAS NO.1421-14-3) is heated to decomposition, it emits toxic fumes of NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	intravenous	80mg/kg (80mg/kg)		Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
dog	LD50	intravenous	80mg/kg (80mg/kg)		Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
human	TDLo	intravenous	5mg/kg (5mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC	British Journal of Anesthesia. Vol. 45, Pg. 1097, 1973.
mouse	LD50	intravenous	113mg/kg (113mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 845, 1980.
rabbit	LD50	intravenous	75mg/kg (75mg/kg)		Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
rat	LD50	intravenous	81mg/kg (81mg/kg)		Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
rat	LD50	oral	> 10gm/kg (10000mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.