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Dextrophan tartrate cas no:143-98-6

Synonyms: 17methyl,tartrate(1:1)(salt),(+)morphinan3o;d3hydroxynmethylmorphinantartrate;dat;dextrophantartrate;DEXTRORPHANDTARTRATE((+)3HYDROXYNMETH;Dextrorphan,TartrateSalt;Dextrorphan,TartrateSalt

Identification
NameDextrophan tartrate
CAS143-98-6
Synonyms17methyl,tartrate(1:1)(salt),(+)morphinan3o;d3hydroxynmethylmorphinantartrate;dat;dextrophantartrate;DEXTRORPHANDTARTRATE((+)3HYDROXYNMETH;Dextrorphan,TartrateSalt;Dextrorphan,TartrateSalt
Molecular FormulaC17H23NO . C4H6O6 . H2O
Molecular Weight407.45746
Chemical Properties
storage temp−70°C
Safety Data

Hazard Xn
Risk R22
Safety

Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Dextrophan tartrate (CAS NO.143-98-6):
Hazard Codes: XnHarmful
Risk Statements: 22  
22:  Harmful if swallowed 


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 42mg/kg (42mg/kg)   "Synthetic Analgesics," Oxford, Pergamon Press, 1966Vol. 2, Pg. 77, 1966.
mouse LD50 oral 385mg/kg (385mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953.
mouse LD50 parenteral 17414ug/kg (17.414mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 11, 1964.
mouse LD50 subcutaneous 350mg/kg (350mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953.
rabbit LD50 intravenous 27500ug/kg (27.5mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: REGIDITY
Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953.
rat LD50 oral 1100mg/kg (1100mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953.
rat LD50 subcutaneous 800mg/kg (800mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953.

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