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Cinchonan-9-ol,10,11-dihydro-6'-methoxy-, (9S)- cas no:1435-55-8

Synonyms: Hydroquinidine(6CI,7CI,8CI);(+)-Hydroquinidine;(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol;10,11-Dihydroquinidine;Dihydroquinidine;

Identification
NameCinchonan-9-ol,10,11-dihydro-6'-methoxy-, (9S)-
CAS1435-55-8
SynonymsHydroquinidine(6CI,7CI,8CI);(+)-Hydroquinidine;(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol;10,11-Dihydroquinidine;Dihydroquinidine;
EINECS(EC#)215-862-5
Molecular FormulaC20H26N2O2
Molecular Weight326.48
Chemical Properties
AppearanceCLEAR, PALE YELLOW
alpha226 o (C=2 IN ETOH)
refractive index1.626
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

A poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.Safety information of Hydroquinidine (CAS NO.1435-55-8):
Hazard Codes  HarmfulXn
Risk Statements 
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements 
36/37 Wear suitable protective clothing and gloves
RIDADR  1544
WGK Germany  3
RTECS  MX3016000
HazardClass  6.1(b)
PackingGroup  III


Toxicity
1.    

orl-rat LD50:369 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),589.
2.    

ivn-rat LD50:32 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),589.
3.    

ivn-mus LD50:56,500 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 84 (1945),184.

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