Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-methyl-, hydrochloride (1:1) cas no:14362-31-3

NamePiperazine,1-[(4-chlorophenyl)phenylmethyl]-4-methyl-, hydrochloride (1:1)
CAS14362-31-3
SynonymsPiperazine,1-(p-chloro-a-phenylbenzyl)-4-methyl-,monohydrochloride (8CI); Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-methyl-, monohydrochloride (9CI);Chlorcyclizine chloride; Chlorcyclizine hydrochloride; Chlorcyclizinemonohydrochloride; Di-Paralene; Histantin; NSC 169496; Perazil
EINECS(EC#)238-335-1
Molecular FormulaC18H22Cl2N2
Molecular Weight337.29

refractive index1.59

Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When Chlorcyclizine hydrochloride (CAS NO.14362-31-3) is heated to decomposition ,it emits very toxic fumes of HCl and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	intraperitoneal	75mg/kg (75mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 213, 1972.
dog	LD50	intraperitoneal	125mg/kg (125mg/kg)		Compilation of LD50 Values of New Drugs.
guinea pig	LD50	intraperitoneal	100mg/kg (100mg/kg)		Compilation of LD50 Values of New Drugs.
mouse	LD50	intraperitoneal	100mg/kg (100mg/kg)		Compilation of LD50 Values of New Drugs.
mouse	LD50	intravenous	35mg/kg (35mg/kg)		Compilation of LD50 Values of New Drugs.
mouse	LD50	oral	300mg/kg (300mg/kg)		Compilation of LD50 Values of New Drugs.
mouse	LD50	subcutaneous	200mg/kg (200mg/kg)		Compilation of LD50 Values of New Drugs.
rat	LD50	intraperitoneal	100mg/kg (100mg/kg)		Compilation of LD50 Values of New Drugs.