2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-, sodium salt (1:1) cas no:144-02-5
Synonyms: 2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-, monosodium salt (9CI);Barbituric acid, 5,5-diethyl-, sodium salt(8CI);Barbital sodium;Barbital soluble;Barbitone sodium;Diethylmalonylureasodium;Embinal;Medinal;Natrinal;Nervoseton;Sodium5,5-diethylbarbiturate;Sodium Veronal;Sodium barbital;Sodium barbitone;Sodium diethylbarbiturate;Soluble barbital;Soprinal;Thyalone;Veronal sodium;4,6(1H,5H)-pyrimidinedione, 5,5-diethyl-2-hydroxy-, sodium salt (1:1);5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione Monosodium Salt;sodium 5,5-diethyl-4,6-dioxo-1,4,5,6-tetrahydropyrimidin-2-olate;
Name2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-, sodium salt (1:1)
CAS144-02-5
Synonyms2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-, monosodium salt (9CI);Barbituric acid, 5,5-diethyl-, sodium salt(8CI);Barbital sodium;Barbital soluble;Barbitone sodium;Diethylmalonylureasodium;Embinal;Medinal;Natrinal;Nervoseton;Sodium5,5-diethylbarbiturate;Sodium Veronal;Sodium barbital;Sodium barbitone;Sodium diethylbarbiturate;Soluble barbital;Soprinal;Thyalone;Veronal sodium;4,6(1H,5H)-pyrimidinedione, 5,5-diethyl-2-hydroxy-, sodium salt (1:1);5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione Monosodium Salt;sodium 5,5-diethyl-4,6-dioxo-1,4,5,6-tetrahydropyrimidin-2-olate;
EINECS(EC#)205-613-9
Molecular FormulaC8H11N2O3Na
Molecular Weight206.17431
Appearancewhite solid.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn: Harmful;
Risk R22
Safety
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Large doses cause marked depression (sometimes preceded by excitation), prolonged coma, and death. Experimental teratogenic and reproductive effects. Allergic skin reactions may occur on contact. Implicated in development of aplastic anemia. Questionable carcinogin with experimental tumorigenic and neoplastigenic data. A truly habit-forming drug. Other experimental reproductive effects. Mutation data reported. Combustible. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also BARBITURATES.
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Hazard Codes: Xn.gif)
Risk Statements:
22: ?Harmful if swallowed?
Safety Statements:
36: ?Wear suitable protective clothing
| 1. |
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sce-ham:emb 100?μg/L
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IJCNAW ?? International Journal of Cancer, 20 (1977),768. |
| 2. |
??? |
orl-rat TDLo:121?g/kg/72W-C:NEO
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CRNGDP ?? Carcinogenesis, 11 (1990),2149. |
| 3. |
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orl-rat LD50:600?mg/kg
|
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ARTODN ?? Archives of Toxicology, 54 (1983),275. |
| 4. |
??? |
scu-rat LDLo:300?mg/kg
|
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JPETAB ?? Journal of Pharmacology and Experimental Therapeutics, 31 (1927),1. |
| 5. |
??? |
ivn-rat LD50:280?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics, 135 (1962),213. |
| 6. |
??? |
orl-mus LD50:800?mg/kg
|
??? |
TXAPA9 ?? Toxicology and Applied Pharmacology, 27 (1974),70. |
| 7. |
??? |
ipr-mus LD50:620?mg/kg
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??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics, 87 (1946),265. |
| 8. |
??? |
scu-mus LD50:700?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics, 109 (1953),268. |
| 9. |
??? |
ivn-mus LD50:830?mg/kg
|
??? |
TXAPA9 ?? Toxicology and Applied Pharmacology, 27 (1974),70. |
| 10. |
??? |
orl-dog LDLo:350?mg/kg
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??? |
27ZWAY ?? Heffter’s Handbuch der Experimentelle Pharmakologie. 1936. |
