Oxalic acid cas no:144-62-7

NameOxalic acid
CAS144-62-7
SynonymsEthanedionic acid; Oxalic acid anhydrous; Refined Oxalic Acid; Anhydrous Oxalic Acid; ethanedioic acid
EINECS(EC#)205-634-3
Molecular FormulaC2H2O4
Molecular Weight90.03

AppearanceOdorless white solid

Hazardclass8

Hazard Xn:Harmful
Risk R21/22
Safety

Poison by subcutaneous route. Moderately toxic by ingestion. A skin and severe eye irritant. Acute oxalic poisoning results from ingestion of a solution of the acid. There is marked corrosion of the mouth, esophagus, and stomach, with symptoms of vomiting, burning abdominal pain, collapse, and sometimes convulsions. Death may follow quickly. The systemic effects are attributed to the removal by the oxalic acid of the calcium in the blood. The renal tubules become obstructed by the insoluble calcium oxalate, and there is profound kidney disturbance. The chief effects of inhalation of the dusts or vapor are severe irritation of the eyes and upper respiratory tract, gastrointestinal disturbances, albuminuria, gradual loss of weight, increasing weakness and nervous system complaints, ulceration of the mucous membranes of the nose and throat, epistaxis, headache, irritation, and nervousness. Oxalic acid has a caustic action on the skin and may cause dermatitis; a case of early gangrene of the fingers resembling that caused by phenol has been described. More severe cases may show albuminuria, chronic cough, vomiting, pain in the back, and gradual emaciation and weakness. The skin lesions are characterized by cracking and fissuring of the skin and the development of slow-healing ulcers. The skin may be bluish in color, and the nails brittle and yellow. Violent reaction with furfuryl alcohol, Ag, NaClO₃, NaOCl. When heated to decomposition it emits acrid smoke and irritating fumes. See also OXALATES.
Hazard Codes:?Xn
Risk Statements: 21/22-63-34?
R21/22:Harmful in contact with skin and if swallowed.?
R34:Causes burns.?
R63:Possible risk of harm to the unborn child.
Safety Statements: 24/25-23-36/37/39-27-26?
S23:Do not breathe vapour.?
S24/25:Avoid contact with skin and eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S27:Take off immediately all contaminated clothing.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.

1.	???	skn-rbt 500?mg/24H MLD	???	85JCAE ?? Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.:?Avicenum,1986,311.
2.	???	eye-rbt 250?μg/24H SEV	???	85JCAE ?? Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.:?Avicenum,1986,311.
3.	???	eye-rbt 100?mg/4S rns SEV	???	FCTOD7 ?? Food and Chemical Toxicology. 20 (1982),573.
4.	???	ipr-mus LD50:270?mg/kg	???	TXCYAC ?? Toxicology. 62 (1990),203.
5.	???	orl-rat LD50:7500?mg/kg	???	TXAPA9 ?? Toxicology and Applied Pharmacology. 42 (1977),417.
6.	???	scu-cat LDLo:112?mg/kg	???	HBAMAK ?? Abdernaldens Handbuch der Biologischen Arbeitsmethoden. 4 (1935),1377.
7.	???	scu-frg LDLo:757?mg/kg	???	HBAMAK ?? Abdernaldens Handbuch der Biologischen Arbeitsmethoden. 4 (1935),1377.