Benzenesulfonamide,4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)- cas no:144-82-1
Synonyms: Sulfanilamide,N1-(5-methyl-1,3,4-thiadiazol-2-yl)- (6CI,7CI,8CI); 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole;2-Sulfanilamido-5-methyl-1,3,4-thiadiazole;4-Amino-N-(5-methyl-[1,3,4]thiadiazol-2-yl)benzenesulfonamide;5-Methyl-2-sulfanilamido-1,3,4-thiadiazole; Ayerlucil; Famet; Lucosil;Methazol; Microsul; N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-aminobenzenesulfonamide;N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; Renasul; Rufol; Salimol;Sulfamethiazole; Sulfamethizol; Sulfamethizole; Sulfamethylthiadiazole;Sulfapyelon; Sulfstat; Sulfurine; Sulphamethizole; Tetracid; Thidicur;Thiosulfil; Thiosulfil Forte; Ultrasul; Urocydal; Urodiaton; Urolucosil;Urosulfin; VK 53
NameBenzenesulfonamide,4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-
CAS144-82-1
SynonymsSulfanilamide,N1-(5-methyl-1,3,4-thiadiazol-2-yl)- (6CI,7CI,8CI); 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole;2-Sulfanilamido-5-methyl-1,3,4-thiadiazole;4-Amino-N-(5-methyl-[1,3,4]thiadiazol-2-yl)benzenesulfonamide;5-Methyl-2-sulfanilamido-1,3,4-thiadiazole; Ayerlucil; Famet; Lucosil;Methazol; Microsul; N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-aminobenzenesulfonamide;N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; Renasul; Rufol; Salimol;Sulfamethiazole; Sulfamethizol; Sulfamethizole; Sulfamethylthiadiazole;Sulfapyelon; Sulfstat; Sulfurine; Sulphamethizole; Tetracid; Thidicur;Thiosulfil; Thiosulfil Forte; Ultrasul; Urocydal; Urodiaton; Urolucosil;Urosulfin; VK 53
EINECS(EC#)205-641-1
Molecular FormulaC9H10 N4 O2 S2
Molecular Weight270.3313
Appearancewhite to pale yellow crystalline powder
refractive index1.686
storage temp2-8°C
Hazard Xi: Irritant;
Risk R43
Safety
Moderately toxic by ingestion and subcutaneous routes. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also SULFONATES.
Hazard Codes:
Xi
Risk Statements:
R43:May cause sensitization by skin contact.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves.
WGK Germany: 2
RTECS: WP0875000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intramuscular |
3668mg/kg (3668mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 388, 1982. |
| mouse |
LD50 |
intraperitoneal |
3290mg/kg (3290mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967. |
| mouse |
LD50 |
intravenous |
1820mg/kg (1820mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 388, 1982. |
| mouse |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 388, 1982. |
| mouse |
LD50 |
subcutaneous |
1210mg/kg (1210mg/kg) |
|
"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 111, 1969. |
| rat |
LD50 |
intramuscular |
4444mg/kg (4444mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 388, 1982. |
| rat |
LD50 |
intravenous |
2710mg/kg (2710mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 388, 1982. |
| rat |
LD50 |
oral |
3500mg/kg (3500mg/kg) |
|
Yakugaku Zasshi. Journal of Pharmacy. Vol. 83, Pg. 778, 1963. |
| rat |
LD50 |
subcutaneous |
> 6560mg/kg (6560mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 388, 1982. |
