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Olean-12-en-29-oicacid, 3-hydroxy-11-oxo-, (3b,18a,20b)- cas no:1449-05-4

Synonyms: 18a-Olean-12-en-30-oic acid, 3b-hydroxy-11-oxo- (6CI,7CI,8CI);18-Isoglycyrrhetinic acid;18a-Glycyrrhetic acid;18a-Glycyrrhetinic acid;NSC 35350;STX 353;b-Glycyrrhetinic acid;

Identification
NameOlean-12-en-29-oicacid, 3-hydroxy-11-oxo-, (3b,18a,20b)-
CAS1449-05-4
Synonyms18a-Olean-12-en-30-oic acid, 3b-hydroxy-11-oxo- (6CI,7CI,8CI);18-Isoglycyrrhetinic acid;18a-Glycyrrhetic acid;18a-Glycyrrhetinic acid;NSC 35350;STX 353;b-Glycyrrhetinic acid;
EINECS(EC#)215-907-9
Molecular FormulaC30H46O4
Molecular Weight470.76
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
 

Hazard Codes of 18alpha-Glycyrrhetinic acid (CAS NO.1449-05-4): HarmfulXn
Risk Statements:
R22:Harmful if swallowed.


Toxicity
1.    

orl-mus LD50:560 mg/kg

    CPBTAL    Chemical and Pharmaceutical Bulletin. 28 (1980),3449.
2.    

ipr-mus LD50:455 mg/kg

    CPBTAL    Chemical and Pharmaceutical Bulletin. 28 (1980),3449.
3.    

ivn-mus LD50:100 mg/kg

    CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#02068 .

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