1,3,5-Naphthalenetrisulfonicacid,8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis- cas no:145-63-1
Synonyms: 1,3,5-Naphthalenetrisulfonicacid,8,8'-[ureylenebis[m-phenylenecarbonylimino(4-methyl-m-phenylene)carbonylimino]]di-(8CI);8,8'-[Ureylenebis[m-phenylenecarbonylimino(4-methyl-m-phenylene)carbonylimino]]di-1,3,5-naphthalenetrisulfonicacid; Farma; Farma 939; Fourneau; Metaret; Naganol; Suramin; Suramine
Name1,3,5-Naphthalenetrisulfonicacid,8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-
CAS145-63-1
Synonyms1,3,5-Naphthalenetrisulfonicacid,8,8'-[ureylenebis[m-phenylenecarbonylimino(4-methyl-m-phenylene)carbonylimino]]di-(8CI);8,8'-[Ureylenebis[m-phenylenecarbonylimino(4-methyl-m-phenylene)carbonylimino]]di-1,3,5-naphthalenetrisulfonicacid; Farma; Farma 939; Fourneau; Metaret; Naganol; Suramin; Suramine
EINECS(EC#)205-658-4
Molecular FormulaC51H40 N6 O23 S6
Molecular Weight1297.33
refractive index1.777
Safety
Moderately toxic by intravenous route. Human systemic effects by intravenous route: eye effects. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of SOx and NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| man |
TDLo |
intravenous |
46mg/kg/5W-I (46mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE |
New England Journal of Medicine. Vol. 314, Pg. 1455, 1986. |
| mouse |
LD50 |
intravenous |
620mg/kg (620mg/kg) |
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
Advances in Pharmacology and Chemotherapy. Vol. 15, Pg. 289, 1978. |
