145040-37-5|Candesartan cilexetilProducts Supply - Chemical intermediates Network

Candesartan cilexetil cas no:145040-37-5

Synonyms: 1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil;

Identification

NameCandesartan cilexetil
CAS145040-37-5
Synonyms1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil;
Molecular FormulaC₃₃H₃₄N₆O₆
Molecular Weight610.67

Chemical Properties

AppearanceWhite crystalline powder
refractive index1.665

Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Hazard Codes:? Harmful Xn
Risk Statements: 20/21/22-36/37/38?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements of Candesartan cilexetil (CAS NO.145040-37-5): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 406, 2000.
mouse	LD50	intraperitoneal	807mg/kg (807mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
mouse	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
rat	LD50	intraperitoneal	940mg/kg (940mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
rat	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,

supplier list

Chuming Pharmaceutical Limited: Tel:; Address: 9th Fl.,Garden Building, Jiuzhou Ave. No.1083, Zhuhai,China

Hangzhou VIWA Co., Ltd.: Tel:0086-571-56836886, 56832058, 56836878; Address: Block B, 5F, Huanglong Hengli Mansion,No.5 Huanglong Road, Hangzhou, China

FAITH EAGLE (LABORATORY) LTD.: Tel:(+86-755) 82851290; Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China

Jiangxi Synergy Pharmaceuticals Co.,Ltd.: Tel:; Address: Jiangxi Fengxin Industrial Park, Fengxin,Jiangxi 330700,P.R.China

Hetero Drugs Ltd.,: Tel:+91-(40)-23704923; Address: H.No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh 500 018,

Nanjing Qida International Trading Co., Ltd: Tel:+86-(25)-8646-0031; Address: B-15A01, 130 Olympic Av., Nanjing, Jiangsu 210019,

Zhejiang Daoqi Industry & Trade Co.,Ltd.: Tel:+86-(576)-88603100; Address: 7F, No.71, Huiyan Lu, Taizhou City, Zhejiang 318000,

ACIC Fine Chemicals Inc.: Tel:+1-(800)-265-6727; Address: 11772 West Sample Road, Coral Springs, Florida 33065,

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

AOKChem Co., Ltd.: Tel:+86-(21)-50791030 / 68712331; Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,

Chongqing Trust Long Co., Ltd.: Tel:+86-(23)-6760-5657, 6791-0421, 6707-4306; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist, Chongqing 401147,

Chemrio International Limited: Tel:+86-(574)-2789-1268, +86-13957895864; Address: Room 611-612 Wante Business Center, No.487 Yangmuqi Road, Hi-tech Park, Ningbo, Zhejiang 315040,

Taizhou Crene Chempharm Co., Ltd.: Tel:+86-(576)-88813233; Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000,

Ronas Chemicals Ind. Co., Ltd.: Tel:+86-(28)-86082869; Address: Rome International Plaza,Room 09A,19th Floor,NO.210,West Yulong Street, Chengdu, Qingyang District, Sichuan 610072,

Anhui Eapearl Chem Co., Ltd.: Tel:86-562-5858458; Address: 358 South Huiihe Road，Tongling city，Anhui Province.P.R.China

Candesartan cilexetil cas no:145040-37-5

Directory

supplier list