145040-37-5|Candesartan cilexetilProducts Supply - Chemical intermediates Network

Candesartan cilexetil cas no:145040-37-5

Synonyms: 1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil;

Identification

NameCandesartan cilexetil
CAS145040-37-5
Synonyms1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil;
Molecular FormulaC₃₃H₃₄N₆O₆
Molecular Weight610.67

Chemical Properties

AppearanceWhite crystalline powder
refractive index1.665

Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Hazard Codes:? Harmful Xn
Risk Statements: 20/21/22-36/37/38?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements of Candesartan cilexetil (CAS NO.145040-37-5): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 406, 2000.
mouse	LD50	intraperitoneal	807mg/kg (807mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
mouse	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
rat	LD50	intraperitoneal	940mg/kg (940mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
rat	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,

supplier list

Hangzhou Starshine Pharmaceutical Co., LTD: Tel:86-571-8696517; Address: Fengqi East Road, Hangzhou, China.

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Depew Fine Chemical Co.,Ltd.: Tel:+86-571-87630650, 87630656, 87630657; Address: Room 202,No.317 Wantang Road,Hangzhou,China

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N-Techem International Co.Ltd.: Tel:; Address: Room 803, B Building, LiYuanShangDu, 39#, 158 Lane, HuanCheng XiLu, Ningbo, Zhejiang, China

Melone Pharmaceutical Co., Ltd.: Tel:; Address: Room 2209锛孨o.232, Jinma Road, Development Zone, Dalian, China

Changzhou United Chemical Co., Ltd. &Changzhou Li...: Tel:; Address: 5/F B Flat, XingBei Building NO. 391 Tongjiang road Changzhou Jiangsu China

Jiangxi Synergy Pharmaceuticals Co.,Ltd.: Tel:; Address: Jiangxi Fengxin Industrial Park, Fengxin,Jiangxi 330700,P.R.China

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Sichuan Huafamei Enterprise Co., Ltd.: Tel:+86-(28)-8618-1366; Address: Floor Block A,Huaxi Building,5 LinYin Road, Chengdu 610041,

Zhongrong Chemical Co. Ltd.: Tel:+86-(576)-8869-8077; Address: 7F, No.71,Huiyan Lu, Taizhou City, Zhejiang 318000,

Hangzhou Pharma & Chem Co., Ltd.: Tel:+86-(571)-87040515; Address: Rm.1201,Qinglian Bldg.No,139 Qingchun Rd, Hangzhou, Zhejiang 310003,

Ningbo Victory & Prosperity Chemistry CO.,LTD.: Tel:+86-(574)-27666767; Address: 21/F, No.11 Bldg, Xin Tian Di, NO 689, Shi Ji Road, NINGBO 315040,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

Candesartan cilexetil cas no:145040-37-5

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