145040-37-5|Candesartan cilexetilProducts Supply - Chemical intermediates Network

Candesartan cilexetil cas no:145040-37-5

Synonyms: 1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil;

Identification

NameCandesartan cilexetil
CAS145040-37-5
Synonyms1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;TCV-116;Atacand;Atacand (TN);1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzoimidazole-4-carboxylate;TCV 116;Candesartancilexetil;
Molecular FormulaC₃₃H₃₄N₆O₆
Molecular Weight610.67

Chemical Properties

AppearanceWhite crystalline powder
refractive index1.665

Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Hazard Codes:? Harmful Xn
Risk Statements: 20/21/22-36/37/38?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements of Candesartan cilexetil (CAS NO.145040-37-5): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 406, 2000.
mouse	LD50	intraperitoneal	807mg/kg (807mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
mouse	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
rat	LD50	intraperitoneal	940mg/kg (940mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,
rat	LD50	oral	> 2gm/kg (2000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 24(Suppl,

supplier list

Saniver Limited: Tel:; Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Hangzhou Starshine Pharmaceutical Co., LTD: Tel:86-571-8696517; Address: Fengqi East Road, Hangzhou, China.

ZHEJIANG YONGNING PHARMACEUTICAL CO.,LTD: Tel:; Address: Meihuajing Road Huangyan City Zhejiang China

Chuming Pharmaceutical Limited: Tel:; Address: 9th Fl.,Garden Building, Jiuzhou Ave. No.1083, Zhuhai,China

Beijing FortuneStar S&T Development Co., Ltd.: Tel:; Address: Zhuyuan 2-2-201, Mingliuhuayuan, Beiqijia, Changping Dist., Beijing, China

ZHEJIANG HOLYPHARM BIOTECH CO.,LTD: Tel:86-533-8585678; Address: Room C 13th Floor, West Wing International Garden, No.160 Tianmushan Road, Xihu District, Hangzhou City, China

Taizhou Zhongrong Chemical Co., Ltd.: Tel:86-576-88603100; Address: 7F, No.71,Huiyan Lu,Jiaojiang Zone,Taizhou City,Zhejiang

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Hangzhou Haichem Co., Ltd.: Tel:+86-571-86025531 86024803; Address: 1218-24, Guangyin Mansion, 42 Fengqi East Road,Hangzhou, China

Hangzhou Cowin Pharma Co., Ltd.: Tel:; Address: B-12F,International Garden,No.158 Tianmushan Road,Hangzhou,China

CHONGQING TRUST LONG CO.,LTD.: Tel:; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist.,Chongqing,China

CIDIC Co.,Ltd.: Tel:; Address: 15/F, HODO International Plaza, 531 Zhongshan Road, Wuxi, China

Zhuhai Sanxin Fine Chemcial Co.,Ltd.: Tel:; Address: 6 Jichang North Road, Jinwan District, Zhuhai 519041 China

Zhejiang Kinglyuan Pharmaceutical Company Limited: Tel:+86-575-82737898; Address: Hangzhou Bay Fine Chemical Industrial Zone, Shangyu, Zhejiang Province

Candesartan cilexetil cas no:145040-37-5

Directory

supplier list