146-56-5|1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, hydrochloride (1:2)Products Supply

1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, hydrochloride (1:2) cas no:146-56-5

Synonyms: fluphenazine dihydrochloride; Fluphenazine HCL

Identification

Name1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, hydrochloride (1:2)
CAS146-56-5
Synonymsfluphenazine dihydrochloride; Fluphenazine HCL
EINECS(EC#)205-674-1
Molecular FormulaC₂₂H₂₈Cl₂F₃N₃OS
Molecular Weight473.983

Chemical Properties

AppearanceOff-white solid
Sensitive Hygroscopic

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard Xn: Harmful;
Risk R36/37/38
Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Human systemic effects by ingestion: musculo-skeletal changes. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl, SO_x, NO_x, and F⁻.
Hazard Codes:
Harmful Xn
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S36:Wear suitable protective clothing.
RIDADR: UN2811
RTECS: TL9800000
HazardClass: 6.1
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intraperitoneal	299mg/kg (299mg/kg)		Pharmazie. Vol. 38, Pg. 749, 1983.
human	TDLo	oral	2800ug/kg/2W- (2.8mg/kg)	musculoskeletal: other changes	British Medical Journal. Vol. 2, Pg. 1071, 1966.
mouse	LD50	intraperitoneal	89mg/kg (89mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 24, 1972.
mouse	LD50	intravenous	56mg/kg (56mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00179,
mouse	LD50	oral	220mg/kg (220mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 24, 1972.

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Andexin industrial Co.,Limited: Tel:86-411-39074598; Address: No.98,Shengli road,,Jinzhou district,

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AFINE CHEMICALS LIMITED: Tel:86-571-85232161; Address: 6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

Nanjing Chemlin Chemical Co., Ltd.: Tel:86-25-83697070; Address: Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

HangZhou Peak Chemical Co.,Ltd: Tel:+86-571-88233073; Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

Hangzhou Starshine Pharmaceutical Co., LTD: Tel:86-571-8696517; Address: Fengqi East Road, Hangzhou, China.

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ORICHEM INTERNATIONAL LTD.: Tel:86-0571-85270505; Address: FLAT E,16/F,1 HUAZHE PLAZA,HANGZHOU,

Wuhan Dahua Weiye Pharmaceutical Co.,Ltd: Tel:86-27-59335372; Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China

Wuhan H.X.K Fine Chemicals Co.,LTD: Tel:86-27-59721024; Address: No. 139, hanyang Road, hubei city， Hubei Prov. China 434000

1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, hydrochloride (1:2) cas no:146-56-5

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