mouse
|
LC50
|
inhalation
|
142mg/m3 (142mg/m3)
|
|
"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.
|
mouse
|
LD50
|
intravenous
|
56mg/kg (56mg/kg)
|
|
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02221,
|
mouse
|
LD50
|
oral
|
6gm/kg (6000mg/kg)
|
|
Journal of Pharmaceutical Sciences. Vol. 56, Pg. 240, 1967.
|
mouse
|
LDLo
|
intramuscular
|
1389mg/kg (1389mg/kg)
|
peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)
behavioral: muscle weakness
|
Annales Pharmaceutiques Francaises. Vol. 14, Pg. 88, 1956.
|
mouse
|
LDLo
|
intraperitoneal
|
174mg/kg (174mg/kg)
|
peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)
behavioral: muscle weakness
|
Annales Pharmaceutiques Francaises. Vol. 14, Pg. 88, 1956.
|
mouse
|
LDLo
|
parenteral
|
347mg/kg (347mg/kg)
|
peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)
|
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 239, Pg. 1091, 1954.
|
rabbit
|
LDLo
|
oral
|
> 5gm/kg (5000mg/kg)
|
|
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
|
rabbit
|
LDLo
|
skin
|
2gm/kg (2000mg/kg)
|
|
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
|
rat
|
LD50
|
intravenous
|
48mg/kg (48mg/kg)
|
behavioral: somnolence (general depressed activity)
gastrointestinal: "hypermotility, diarrhea"
|
"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.
|
rat
|
LD50
|
oral
|
1268mg/kg (1268mg/kg)
|
behavioral: somnolence (general depressed activity)
gastrointestinal: "hypermotility, diarrhea"
|
"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.
|
rat
|
LD50
|
subcutaneous
|
3082mg/kg (3082mg/kg)
|
behavioral: somnolence (general depressed activity)
gastrointestinal: "hypermotility, diarrhea"
|
"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.
|