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Dantrolene sodium salt cas no:14663-23-1

Synonyms: 2,4-Imidazolidinedione,1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt (9CI);Hydantoin, 1-[[5-(p-nitrophenyl)furfurylidene]amino]-, sodium salt (8CI);Dantrium;Dantrolene sodium;F 440;Sodium dantrolene;

Identification
NameDantrolene sodium salt
CAS14663-23-1
Synonyms2,4-Imidazolidinedione,1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt (9CI);Hydantoin, 1-[[5-(p-nitrophenyl)furfurylidene]amino]-, sodium salt (8CI);Dantrium;Dantrolene sodium;F 440;Sodium dantrolene;
EINECS(EC#)238-706-8
Molecular FormulaC14H9N4O5Na
Molecular Weight336.23
Chemical Properties
AppearanceCOA
Safety Data

Safety

Moderately toxic by intraperitoneal and ingestion routes. Human systemic effects by ingestion: anorexia (human), hepatitis, nausea or vomiting, somnolence. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and Na2O.
Safety Statements: 22-24/25
22:  Do not breathe dust 
24/25:  Avoid contact with skin and eyes
WGK Germany: 2
RTECS: MU3875000


Toxicity
1.    

orl-hmn TDLo:320 mg/kg:BAH,GIT

    JAMAAP    JAMA, Journal of the American Medical Association. 231 (1975),662.
2.    

orl-wmn LDLo:600 mg/kg:GIT,SYS

    NYSJAM    New York State Journal of Medicine. 77 (1977),1759.
3.    

orl-rat LD50:7431 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668.
4.    

ipr-rat LD50:413 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668.
5.    

orl-mus LD50:1188 mg/kg

    JPMSAE    Journal of Pharmaceutical Sciences. 69 (1980),327.
6.    

ipr-mus LD50:534 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668.

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