147-24-0|Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1)Products Supply

Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1) cas no:147-24-0

Synonyms: Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (9CI);2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride;Alledryl;Allergina;Amidryl;Bagodryl;Bena;Benadrilhydrochloride;Benison;Benodine;Benzantin;Benzhydrol b-dimethylaminoethyl ether hydrochloride;Denydryl;Dibondrin;Dimedrol;Diphantine;Fenylhist;

Identification

NameEthanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1)
CAS147-24-0
SynonymsEthanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (9CI);2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride;Alledryl;Allergina;Amidryl;Bagodryl;Bena;Benadrilhydrochloride;Benison;Benodine;Benzantin;Benzhydrol b-dimethylaminoethyl ether hydrochloride;Denydryl;Dibondrin;Dimedrol;Diphantine;Fenylhist;
EINECS(EC#)205-687-2
Molecular FormulaC₁₇H₂₁NO^.HCl
Molecular Weight291.82

Chemical Properties

AppearanceWhite Crystalline powder
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion or skin contact: arrhythmias, ataxia, blood pressure elevation, convulsions, distorted perceptions, eye effects, and hallucinations. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NO_x and HCl.
Hazard Codes:? Harmful Xn
Risk Statements: 22?
R22:Harmful if swallowed.
Safety Statements: 36?
S36:Wear suitable protective clothing.
RIDADR: 2811
WGK Germany: 3
RTECS of Benzantin hydrochloride? (CAS NO.147-24-0): KR7000000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	12500ug/kg (12.5mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)	Journal of Pediatrics. Vol. 90, Pg. 1017, 1977.
child	TDLo	skin	60mg/kg/6H-I (60mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: ATAXIA	Clinical Pediatrics Vol. 25, Pg. 163, 1986.
dog	LD50	intravenous	24mg/kg (24mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947.
guinea pig	LD50	intraperitoneal	75mg/kg (75mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 83, Pg. 120, 1945.
guinea pig	LD50	oral	280mg/kg (280mg/kg)	?	Journal of Allergy. Vol. 27, Pg. 57, 1956.
guinea pig	LD50	subcutaneous	40mg/kg (40mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 72, 1955.
hamster	LD50	intravenous	18mg/kg (18mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Journal of Pharmacology and Experimental Therapeutics. Vol. 97, Pg. 371, 1949.
mammal (species unspecified)	LD50	intraperitoneal	80mg/kg (80mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 328, 1953.
man	TDLo	oral	10714ug/kg (10.714mg/kg)	AUTONOMIC NERVOUS SYSTEM: PARASYMPATHOLYTIC BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION	American Journal of Emergency Medicine. Vol. 4, Pg. 369, 1986.
mouse	LD50	intraperitoneal	56mg/kg (56mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Journal of Pharmacology and Experimental Therapeutics. Vol. 112, Pg. 318, 1954.
mouse	LD50	intravenous	20mg/kg (20mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 72, 1955.
mouse	LD50	oral	164mg/kg (164mg/kg)	?	Drugs in Japan Vol. -, Pg. 550, 1995.
mouse	LD50	subcutaneous	99200ug/kg (99.2mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 33, 1958.
pigeon	LD50	intramuscular	63mg/kg (63mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 140, 1957.
rabbit	LD50	intravenous	10mg/kg (10mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: EXCITEMENT	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 150, 1945.
rat	LD50	intraperitoneal	82mg/kg (82mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 102, Pg. 250, 1951.
rat	LD50	intravenous	35mg/kg (35mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 2769, 1984.
rat	LD50	oral	500mg/kg (500mg/kg)	?	Drugs in Japan Vol. 6, Pg. 334, 1982.
rat	LD50	subcutaneous	201mg/kg (201mg/kg)	?	Yakugaku Zasshi. Journal of Pharmacy. Vol. 81, Pg. 261, 1961.
women	TDLo	oral	83mg/kg (83mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)	Critical Care Medicine. Vol. 16, Pg. 1161, 1988.

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Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1) cas no:147-24-0

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