Acetamide,N,N'-1,8-octanediylbis[2,2-dichloro- cas no:1477-57-2

NameAcetamide,N,N'-1,8-octanediylbis[2,2-dichloro-
CAS1477-57-2
SynonymsAcetamide,N,N'-octamethylenebis[2,2-dichloro- (6CI,7CI,8CI); Bis-Diamine; Fertilysin;Fertilysine; N,N'-Bis(dichloroacetyl)-1,8-diaminooctane;N,N'-Bis(dichloroacetyl)-1,8-octamethylenediamine;N,N'-Octamethylenebis(2,2-dichloroacetamide); NSC 59354; Win 18441; Win 18446
EINECS(EC#)216-033-0
Molecular FormulaC12H20 Cl4 N2 O2
Molecular Weight366.14

refractive index1.503

Safety

Safety Statements of N,N'-bis(dichloroacetyl)-1,8-diaminooctane (CAS NO.1477-57-2): 24/25 
S24/25: Avoid contact with skin and eyes.
Poison by intraperitoneal route. Human systemic effects by ingestion: nausea and vomiting. Human reproductive effects by ingestion: changes in spermatogenesis. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	943mg/kg/50D (943mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	"Agents Affecting Fertility, a Symposium, 1964," Austin, C.R., and J.S. Perry, eds., Boston, Little, Brown & Co., 1965Vol. -, Pg. 93, 1965.
mouse	LD50	oral	> 16gm/kg (16000mg/kg)		Toxicology and Applied Pharmacology. Vol. 2, Pg. 715, 1960.
mouse	LDLo	intraperitoneal	150mg/kg (150mg/kg)		Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.