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1-Butanone,1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]- cas no:1480-19-9

Synonyms: Butyrophenone,4'-fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]- (6CI,7CI,8CI); 2028 MD;4-[4-(o-Methoxyphenyl)-1-piperazinyl]-p-fluorobutyrophenone;4'-Fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone; Anti-Pica;Fluanison; Fluanisone; Haloanison; Haloanisone; MD 2028; NSC 170977; R 2028; R2167; Sedalande; p-Fluoro-g-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone; g-(4-o-Methoxyphenylpiperazino)-4-fluorobutyrophenone

Identification
Name1-Butanone,1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]-
CAS1480-19-9
SynonymsButyrophenone,4'-fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]- (6CI,7CI,8CI); 2028 MD;4-[4-(o-Methoxyphenyl)-1-piperazinyl]-p-fluorobutyrophenone;4'-Fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone; Anti-Pica;Fluanison; Fluanisone; Haloanison; Haloanisone; MD 2028; NSC 170977; R 2028; R2167; Sedalande; p-Fluoro-g-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone; g-(4-o-Methoxyphenylpiperazino)-4-fluorobutyrophenone
EINECS(EC#)216-038-8
Molecular FormulaC21H25 F N2 O2
Molecular Weight356.48
Chemical Properties
refractive index1.557
Safety Data

Safety

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of F and NOx.


Toxicity
1.    

orl-rat TDLo:132 mg/kg (15D preg):TER

    PJPPAA    Polish Journal of Pharmacology and Pharmacy. 32 (1980),199.
2.    

scu-rat LD50:420 mg/kg

    MDCHAG    Medicinal Chemistry: A Series of Monographs. 4 (2)(1967),199.
3.    

orl-mus LD50:550 mg/kg

    APPHAX    Acta Poloniae Pharmaceutica. 40 (1983),159.
4.    

ipr-mus LD50:200 mg/kg

    FRPSAX    Farmaco, Edizione Scientifica. 35 (1980),605.

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