4H-1,3,2-Benzodioxabismin-4-one,2-hydroxy- cas no:14882-18-9

Name4H-1,3,2-Benzodioxabismin-4-one,2-hydroxy-
CAS14882-18-9
SynonymsBismuth,(2-hydroxybenzoato-O1,O2)oxo-;Bismuth, oxo(salicylato)- (7CI,8CI);Basicbismuth salicylate;Bismuth oxysalicylate;Peptosil;
EINECS(EC#)238-953-1
Molecular FormulaC₇H₅BiO₄
Molecular Weight363.10052

Appearancewhite to off-white crystalline powder

Hazard UN NO.
Safety A poison by ingestion. Human systemic effects. When heated to decomposition it emits toxic vapors of Bi.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

EB2985000

CHEMICAL NAME :

Bismuth, oxo(salicylato)-

CAS REGISTRY NUMBER :

14882-18-9

LAST UPDATED :

199504

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C7-H5-Bi-O4

MOLECULAR WEIGHT :

362.10

WISWESSER LINE NOTATION :

QR BVO-BI-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

60 mg/kg/26W-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :

AJCPAI American Journal of Clinical Pathology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1931- Volume(issue)/page/year: 14,392,1944

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

14480 ug/kg/9D-I

TOXIC EFFECTS :

Musculoskeletal - joints Skin and Appendages - dermatitis, allergic (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase

REFERENCE :

ADSYAF Archives of Dermatology and Syphilology. (Chicago, IL) V.1-62, 1920-50. For publisher information, see ARDEAC. Volume(issue)/page/year: 41,1076,1940

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

17 mg/kg/5W-I

TOXIC EFFECTS :

Gastrointestinal - other changes

REFERENCE :

AJSGA3 American Journal of Syphilis, Gonorrhea and Venereal Diseases. (St. Louis, MO) V.20-38, 1936-54. Discontinued. Volume(issue)/page/year: 26,84,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80378 No. of Facilities: 96 (estimated) No. of Industries: 1 No. of Occupations: 8 No. of Employees: 3666 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80378 No. of Facilities: 405 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 4036 (estimated) No. of Female Employees: 2022 (estimated)