14899-36-6|Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11b,16a)-Products Supply

Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11b,16a)- cas no:14899-36-6

Synonyms: Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 21-palmitate (6CI,8CI);Palmitic acid, 21-ester with 9-fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione (8CI);Dexamethasone 21-palmitate; Dexamethasone palmitate; Limethason; Limethasone;Lipotalon

Identification

NamePregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11b,16a)-
CAS14899-36-6
SynonymsPregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 21-palmitate (6CI,8CI);Palmitic acid, 21-ester with 9-fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione (8CI);Dexamethasone 21-palmitate; Dexamethasone palmitate; Limethason; Limethasone;Lipotalon
Molecular FormulaC38H59 F O6
Molecular Weight630.97

Chemical Properties

refractive index1.537

Safety Data

Safety

An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F⁻.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 160mg/kg (160mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 3998, 1985.
mouse	LD50	intravenous	300mg/kg (300mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
mouse	LD50	oral	510mg/kg (510mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
mouse	LD50	subcutaneous	120mg/kg (120mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
rat	LD50	intravenous	88mg/kg (88mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
rat	LD50	oral	315mg/kg (315mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.
rat	LD50	subcutaneous	90mg/kg (90mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 544, 1988.

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Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11b,16a)- cas no:14899-36-6

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