Calcium folinatc cas no:1492-18-8
Synonyms: Folinic acid Calcium salt; calcium folinate; Folinic acid calcium salt USP28; Calcium leucovorin; LeucovorinCalcium; CALCIUM FOLINATE(FOLINIC ACID)(RG); Folinic acid; Calcium Levofolinate; Leucovorin Calcium; calcium2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl] aminopentanedioate; L-Calcium Folinate
NameCalcium folinatc
CAS1492-18-8
SynonymsFolinic acid Calcium salt; calcium folinate; Folinic acid calcium salt USP28; Calcium leucovorin; LeucovorinCalcium; CALCIUM FOLINATE(FOLINIC ACID)(RG); Folinic acid; Calcium Levofolinate; Leucovorin Calcium; calcium2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl] aminopentanedioate; L-Calcium Folinate
EINECS(EC#)216-082-8
Molecular FormulaC20H21CaN7O7
Molecular Weight511.5
Appearanceyellow crystalline powder
storage tempStore in a tightly closed container. Keep under an argon blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from light and air.
Hazard Xn:Harmful
Risk R36/37/38;R42/43
Safety
Hazard Codes:?
Xn
Risk Statements about Folinic acid (CAS No.1492-18-8):
R42/43: May cause sensitization by inhalation and skin contact.?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements:
S22: Do not breathe dust.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36: Wear suitable protective clothing.?
S36/37: Wear suitable protective clothing and gloves.
Attention:
1. Storage: Store in a tightly closed container. Keep under an argon blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 °C). Store protected from light and air.
2. Handling: Wash hands before eating. Use only in a well ventilated area. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Keep container tightly closed. Store protected from light. Use and store under nitrogen. Store and handle protected from air. Wash clothing before reuse. Discard contaminated shoes.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
1036mg/kg (1036mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992. |
| mouse |
LD50 |
intravenous |
732mg/kg (732mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 910, 1982. |
| mouse |
LD50 |
oral |
> 7gm/kg (7000mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992. |
| rat |
LD50 |
intraperitoneal |
1063mg/kg (1063mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992. |
| rat |
LD50 |
oral |
> 8gm/kg (8000mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992. |
