Saquinavir mesylate cas no:149845-06-7
Synonyms: Saquinavir mesylate [USAN];Saquinavir mesilate;Butanediamide, N1-(3-(3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (3S-(2(1R*(R*),2S*),3alpha,4aalpha,8aalpha))-;Invirase (TN);Saquinavir mesylate; Ro 31-8959 [AmFAR Tx Dir 1993;6(4)];(2S)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-[(3S)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]butan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide;(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide; methanesulfonic acid;Saquinavir mesylate (USP);Invirase;(S)-N-((alphaS)-alpha-((1R)-2-((3S,4aS,8aS)-3-(tert-Butylcarbamoyl)octahydro-2(1H)-isoquinolyl)-1-hydroxyethyl)phenethyl)-2-quinaldamidosuccinamide monomethanesulfonate (salt);Saquinavir mesylate (AIDS Initiative);(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide;SQV;Saquinavir mesilate (JAN);Ro 318959;(S)-N-((alphaS)-alpha-((1R)-3S,4aS,8aS)-3-(tert-Butylcarbaoyl)octahydro-2(1H)-isoquinolyl)-1-hydroxyethyl)phenethyl)-2-quinaldamidosuccinam ide monomethanesulfonate (salt);Butanediamide, N(sup 1)-(3-(3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (3S-(2(1R*(R*),2S*),3alpha,4abeta,8abeta))-, monomethanesulfonate (salt);Ro-31-8959;Butanediamide, N1-((1S,2R)-3-((3S,4aS,8aS)-3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (2S)-;Saquinavir monomethanesulfonate salt;Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-;Saquinavir [USAN];
NameSaquinavir mesylate
CAS149845-06-7
SynonymsSaquinavir mesylate [USAN];Saquinavir mesilate;Butanediamide, N1-(3-(3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (3S-(2(1R*(R*),2S*),3alpha,4aalpha,8aalpha))-;Invirase (TN);Saquinavir mesylate; Ro 31-8959 [AmFAR Tx Dir 1993;6(4)];(2S)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-[(3S)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]butan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide;(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide; methanesulfonic acid;Saquinavir mesylate (USP);Invirase;(S)-N-((alphaS)-alpha-((1R)-2-((3S,4aS,8aS)-3-(tert-Butylcarbamoyl)octahydro-2(1H)-isoquinolyl)-1-hydroxyethyl)phenethyl)-2-quinaldamidosuccinamide monomethanesulfonate (salt);Saquinavir mesylate (AIDS Initiative);(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide;SQV;Saquinavir mesilate (JAN);Ro 318959;(S)-N-((alphaS)-alpha-((1R)-3S,4aS,8aS)-3-(tert-Butylcarbaoyl)octahydro-2(1H)-isoquinolyl)-1-hydroxyethyl)phenethyl)-2-quinaldamidosuccinam ide monomethanesulfonate (salt);Butanediamide, N(sup 1)-(3-(3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (3S-(2(1R*(R*),2S*),3alpha,4abeta,8abeta))-, monomethanesulfonate (salt);Ro-31-8959;Butanediamide, N1-((1S,2R)-3-((3S,4aS,8aS)-3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (2S)-;Saquinavir monomethanesulfonate salt;Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-;Saquinavir [USAN];
Molecular FormulaC38H50N6O5.CH4O3S
Molecular Weight766.94646
Appearancewhite or pale yellow powder
Hazard Moderately toxic by ingestion.
Safety
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx and SOx.
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orl-rat LD :>5 g/kg
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YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),2183. |
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orl-mus LD :>5 g/kg
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YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),2183. |
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ivn-mus LD :>20 mg/kg
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YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),2183. |
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orl-mky LD :>1680 mg/kg
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YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 40 (1998),2183. |
