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Hazard Cholinesterase inhibitor.
Safety
Poison by intraperitoneal route. Moderately toxic by ingestion and skin contact. A cholinesterase inhibitor. Combustible when exposed to heat or flame. Can react vigorously with oxidizing materials. When heated to decomposition it emits highly toxic fumes of POx and SOx.Safety information of S,S,S-Tributyl trithiophosphite (CAS NO.150-50-5):
RIDADR 3278
HazardClass 6.1(b)
PackingGroup III
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | oral | 850mg/kg (850mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 27(8), Pg. 97, 1962. | |
mouse | LD50 | intraperitoneal | 1400mg/kg (1400mg/kg) | Biochemical Pharmacology. Vol. 12, Pg. 73, 1963. | |
mouse | LD50 | oral | 635mg/kg (635mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 27(8), Pg. 97, 1962. | |
rabbit | LD50 | oral | 170mg/kg (170mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 27(8), Pg. 97, 1962. | |
rabbit | LD50 | skin | > 4600mg/kg (4600mg/kg) | Pesticide Manual. Vol. 8, Pg. 819, 1987. | |
rat | LD50 | intraperitoneal | 70mg/kg (70mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1117, 1986. | |
rat | LD50 | oral | 910mg/kg (910mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969. | |
rat | LD50 | skin | 615mg/kg (615mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
rat | LD50 | unreported | 350mg/kg (350mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 308, 1971. |
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