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Tricyclo[3.3.1.13,7]decane-1-methanamine,a-methyl-, hydrochloride (1:1) cas no:1501-84-4

Synonyms: 1-Adamantanemethylamine,a-methyl-, hydrochloride(7CI,8CI);Tricyclo[3.3.1.13,7]decane-1-methanamine, a-methyl-, hydrochloride (9CI);1-(1-Aminoethyl)adamantane hydrochloride;EXP 126;Flumadine;JP 61;Meradan;Meradane;NSC 206764;Roflual;alpha-Methyl-1-adamantanemethylaminehydrochloride;Rimantadine HCl;

Identification
NameTricyclo[3.3.1.13,7]decane-1-methanamine,a-methyl-, hydrochloride (1:1)
CAS1501-84-4
Synonyms1-Adamantanemethylamine,a-methyl-, hydrochloride(7CI,8CI);Tricyclo[3.3.1.13,7]decane-1-methanamine, a-methyl-, hydrochloride (9CI);1-(1-Aminoethyl)adamantane hydrochloride;EXP 126;Flumadine;JP 61;Meradan;Meradane;NSC 206764;Roflual;alpha-Methyl-1-adamantanemethylaminehydrochloride;Rimantadine HCl;
Molecular FormulaC12H22ClN
Molecular Weight215.77
Chemical Properties
Appearancewhite crystalline solid
Safety Data

Hazard Xn:Harmful
Risk R22

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU4717000
CHEMICAL NAME :
1-Adamantanemethylamine, alpha-methyl-, hydrochloride
CAS REGISTRY NUMBER :
1501-84-4
LAST UPDATED :
199803
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H21-N.Cl-H
MOLECULAR WEIGHT :
215.80
WISWESSER LINE NOTATION :
L66 B6/B-H/DI A B- C 1B ITJ BYZ1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 28(9),23,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
135 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,798,1977

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