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Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',4',5',7'-tetrabromo-3',6'-dihydroxy- cas no:15086-94-9

Synonyms: Fluorescein,2',4',5',7'-tetrabromo- (7CI,8CI);3,6-Dihydroxy-2,4,5,7-tetrabromospiro[xanthene-9,3'-phthalide];C.I. 45380:2;C.I. Solvent Red 43;D and C Red No. 21;C Red No. 21;Eosin Y spirit soluble;Eosin acid;Eosine acid;Japan Red 223;

Identification
NameSpiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',4',5',7'-tetrabromo-3',6'-dihydroxy-
CAS15086-94-9
SynonymsFluorescein,2',4',5',7'-tetrabromo- (7CI,8CI);3,6-Dihydroxy-2,4,5,7-tetrabromospiro[xanthene-9,3'-phthalide];C.I. 45380:2;C.I. Solvent Red 43;D and C Red No. 21;C Red No. 21;Eosin Y spirit soluble;Eosin acid;Eosine acid;Japan Red 223;
EINECS(EC#)239-138-3
Molecular FormulaC20H8Br4O5
Molecular Weight691.85418
Chemical Properties
Appearanceorange to red powder
refractive index1.757
storage tempKeep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Safety Data

Hazard Not regulated UN NO.
Risk R36

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5800000
CHEMICAL NAME :
Fluorescein, 2',4',5',7'-tetrabromo-
CAS REGISTRY NUMBER :
15086-94-9
BEILSTEIN REFERENCE NO. :
0063410
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C20-H8-Br4-O5
MOLECULAR WEIGHT :
647.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
2 mg/disc
REFERENCE :
TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- Volume(issue)/page/year: 27,153,1976 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,183,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,183,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0363 No. of Facilities: 347 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 7340 (estimated) No. of Female Employees: 1584 (estimated)

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