151-73-5|Betamethasone 21-phosphate disodiumProducts Supply

Betamethasone 21-phosphate disodium cas no:151-73-5

Synonyms: Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11b,16b)- (9CI);Bentelan;Betamethasone 21-phosphate disodium salt;Betnesol;Celestan solubile;Disodium betamethasone 21-phosphate;Durabetason;NSC 90616;Steronema;Vista-Methasone;

Identification

NameBetamethasone 21-phosphate disodium
CAS151-73-5
SynonymsPregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11b,16b)- (9CI);Bentelan;Betamethasone 21-phosphate disodium salt;Betnesol;Celestan solubile;Disodium betamethasone 21-phosphate;Durabetason;NSC 90616;Steronema;Vista-Methasone;
EINECS(EC#)205-797-0
Molecular FormulaC₂₂H₂₈FNa₂O₈P
Molecular Weight516.41

Chemical Properties

Appearancewhite powder

Safety Data

Hazard Xn:Harmful
Risk R22
Safety

The safety information of Betamethasone disodium phosphate (CAS NO.151-73-5) is as follows:
Hazard Codes: Xn
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 36
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: TU4056500
Moderately toxic by ingestion and other routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of F⁻, PO_x and Na₂O.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1166mg/kg (1166mg/kg)		Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.
mouse	LD50	intravenous	1304mg/kg (1304mg/kg)		Drugs in Japan Vol. -, Pg. 1075, 1990.
mouse	LD50	oral	1607mg/kg (1607mg/kg)		Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.
mouse	LD50	subcutaneous	1363mg/kg (1363mg/kg)		Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.
rat	LD50	intramuscular	1291mg/kg (1291mg/kg)		Drugs in Japan Vol. -, Pg. 1075, 1990.
rat	LD50	intraperitoneal	1179mg/kg (1179mg/kg)		Drugs in Japan Vol. -, Pg. 1075, 1990.
rat	LD50	intravenous	1276mg/kg (1276mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 2117, 1979.
rat	LD50	oral	1877mg/kg (1877mg/kg)		Drugs in Japan Vol. -, Pg. 1075, 1990.
rat	LD50	subcutaneous	1265mg/kg (1265mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 52, Pg. 105, 1996.

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Betamethasone 21-phosphate disodium cas no:151-73-5

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