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Norfenefrine hydrochloride cas no:15308-34-6

Synonyms: alpha-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride; DL-Norphenylephrine hydrochloride

Identification
NameNorfenefrine hydrochloride
CAS15308-34-6
Synonymsalpha-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride; DL-Norphenylephrine hydrochloride
EINECS(EC#)239-351-1
Molecular FormulaC8H11NO2.HCl;C8H12ClNO2
Molecular Weight189.64
Chemical Properties
AppearanceWhite solid.
storage tempStore in a cool, dry place. Store in a tightly closed container.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Safety Data

Hazard Xn
Risk R22
Safety

Hazard Codes of Norfenefrine hydrochloride (CAS NO.15308-34-6): HarmfulXn
Risk Statements: 22 
R22: Harmful if swallowed.
Safety Statements: 22 
S22: Do not breathe dust.
WGK Germany: 3
RTECS DN7400000
HazardClass IRRITANT
Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and HCl.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 645mg/kg (645mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
mouse LD50 intravenous 148mg/kg (148mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
mouse LD50 oral 3300mg/kg (3300mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
mouse LD50 subcutaneous 700mg/kg (700mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
rat LD50 intraperitoneal 32mg/kg (32mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
rat LD50 intravenous 17400ug/kg (17.4mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
rat LD50 oral 390mg/kg (390mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.
rat LD50 subcutaneous 28mg/kg (28mg/kg)   Drugs in Japan Vol. 6, Pg. 569, 1982.

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