Pyridinium,3-[[(dimethylamino)carbonyl]oxy]-1-methyl- cas no:155-97-5

NamePyridinium,3-[[(dimethylamino)carbonyl]oxy]-1-methyl-
CAS155-97-5
SynonymsPyridinium,3-hydroxy-1-methyl-, dimethylcarbamate (6CI); Pyridinium, 3-hydroxy-1-methyl-,dimethylcarbamate (ester) (8CI); Pyridostigmine
Molecular FormulaC9H13 N2 O2
Molecular Weight181.24

Safety

Poison by ingestion, intramuscular, and intraperitoneal routes. When Pyridostigmine (CAS NO.155-97-5) is heated to decomposition, it emits toxic fumes of NO_x. See also CARBAMATES and ESTERS.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intramuscular	1867ug/kg (1.867mg/kg)		Journal of Medicinal Chemistry. Vol. 33, Pg. 577, 1990.
mouse	LD50	intraperitoneal	2700ug/kg (2.7mg/kg)		Fundamental and Applied Toxicology. Vol. 1, Pg. 217, 1981.
mouse	LD50	subcutaneous	3300ug/kg (3.3mg/kg)		Acta Pharmacologica et Toxicologica. Vol. 45, Pg. 9, 1979.
rabbit	LD50	intramuscular	2800ug/kg (2.8mg/kg)		Drug and Chemical Toxicology. Vol. 3, Pg. 319, 1980.
rabbit	LD50	oral	53900ug/kg (53.9mg/kg)		Drug and Chemical Toxicology. Vol. 3, Pg. 319, 1980.
rat	LD50	intramuscular	2790ug/kg (2.79mg/kg)		Drug and Chemical Toxicology. Vol. 1, Pg. 355, 1978.