Pancuronium bromide cas no:15500-66-0
Synonyms: 5a-Androstane-3a,17b-diol, 2b,16b-bis(1-methylpiperidinio)-,dibromide, diacetate (8CI);1,1'-(3a,17b-Dihydroxy-5a-androstan-2b,16b-ylene)bis[1-methylpiperidinium]dibromide diacetate;Mioblock;NA 97;NSC 293162;Org NA 97;Pancuronium;Pancuronium dibromide;Pavulon;
NamePancuronium bromide
CAS15500-66-0
Synonyms5a-Androstane-3a,17b-diol, 2b,16b-bis(1-methylpiperidinio)-,dibromide, diacetate (8CI);1,1'-(3a,17b-Dihydroxy-5a-androstan-2b,16b-ylene)bis[1-methylpiperidinium]dibromide diacetate;Mioblock;NA 97;NSC 293162;Org NA 97;Pancuronium;Pancuronium dibromide;Pavulon;
EINECS(EC#)239-532-5
Molecular FormulaC35H60Br2N2O4
Molecular Weight732.68
AppearanceWhite to near-white, hydroscopic crystalline powder with no odor.
storage tempPancuronium bromide should be stored under refrigeration at 2-8C. Keep container tightly closed.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn:Harmful;
Risk R22
Safety
A human poison by intravenous route. Poison experimentally by intravenous, subcutaneous, and intraperitoneal routes. Human systemic effects by intravenous route: chronic pulmonary edema, hemorrhage. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and Br−.
Hazard Codes:Xn
Xn: Harmful
Risk Statements
R22: Harmful if swallowed.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TN4930000
F: 10-21-33
HazardClass: 6.1(b)
PackingGroup: III
| 1. |
|
ivn-man LDLo:143 µg/kg:BLD,PUL
|
|
JATOD3 Journal of Analytical Toxicology. 4 (1980),275. |
| 2. |
|
orl-rat LD50:202 mg/kg
|
|
SKKNAJ Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories 22 (1970),187. |
| 3. |
|
ipr-rat LD50:479 µg/kg
|
|
SKKNAJ Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories 22 (1970),187. |
| 4. |
|
scu-rat LD50:436 µg/kg
|
|
SKKNAJ Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories 22 (1970),187. |
| 5. |
|
ivn-rat LD50:153 µg/kg
|
|
DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),353. |
| 6. |
|
orl-mus LD50:21,200 µg/kg
|
|
SKKNAJ Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories 22 (1970),187. |
| 7. |
|
ivn-rat LD50:153 µg/kg
|
|
NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),353. |
| 8. |
|
ipr-mus LD50:128 µg/kg
|
|
OYYAA2 Oyo Yakuri. Pharmacometrics. 5 (1971),715. |
| 9. |
|
scu-mus LD50:167 µg/kg
|
|
NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),353. |
