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β-PHENYLETHYLHYDRAZINE SULFATE cas no:156-51-4

Synonyms: phenelzinehydrogensulphate

Identification
Nameβ-PHENYLETHYLHYDRAZINE SULFATE
CAS156-51-4
Synonymsphenelzinehydrogensulphate
EINECS(EC#)205-856-0
Molecular FormulaC8H12N2•H2O4S
Molecular Weight234.27
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn
Safety

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: wakefulness, blood pressure lowering, constipation, hepatitis, fibrous hepatitis. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. Used as a drug for the treatment of depression. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes HarmfulXn
Risk Statements 22
R22:Harmful if swallowed.
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS MV8750000
HazardClass 6.1(b)
PackingGroup III


Toxicity
1.    

mma-sat 800 µg/plate

    NEZAAQ    Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. 33 (1978),474.
2.    

dnr-esc 4300 nmol/plate

    JTEHD6    Journal of Toxicology and Environmental Health. 9 (1982),287.
3.    

orl-mus TDLo:28 g/kg/77W-C:NEO

    CNREA8    Cancer Research. 36 (1976),917.
4.    

orl-hmn TDLo:1070 µg/kg/D:CNS,GIT,CVS

    34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,461.
5.    

orl-man TDLo:46 mg/kg/10W-I:LIV,

    AJMEAZ    American Journal of Medicine. 80 (1986),689.
6.    

orl-wmn TDLo:18 mg/kg

    ANASAB    Anaesthesia. 41 (1986),53.
7.    

orl-rat LD50:210 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),899.
8.    

orl-mus LD50:156 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),899.
9.    

ipr-mus LD50:162 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 18 (1975),20.
10.    

scu-mus LD50:125 mg/kg

    JOENAK    Journal of Endocrinology. 30 (1964),205.
 

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