1H-Pyrrole-2-carboxylicacid,(3S,4R,4aR,6S,6aS,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-ylester cas no:15662-33-6
Synonyms: Ryanodine(6CI,7CI,8CI);Ryanodol, 3-(1H-pyrrole-2-carboxylate);(+)-Ryanodine;1H-Pyrrole-2-carboxylic acid,dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-ylester, [3S-(3a,4b,4aS*,6a,6aa,7a,8b,8aa,8bb,9b,9aa)]-;Ryanex;Ryania;Ryania (pesticide);Ryanicide;Ryanodin;
Name1H-Pyrrole-2-carboxylicacid,(3S,4R,4aR,6S,6aS,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-ylester
CAS15662-33-6
SynonymsRyanodine(6CI,7CI,8CI);Ryanodol, 3-(1H-pyrrole-2-carboxylate);(+)-Ryanodine;1H-Pyrrole-2-carboxylic acid,dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-ylester, [3S-(3a,4b,4aS*,6a,6aa,7a,8b,8aa,8bb,9b,9aa)]-;Ryanex;Ryania;Ryania (pesticide);Ryanicide;Ryanodin;
EINECS(EC#)239-732-2
Molecular FormulaC25H35 N O9
Molecular Weight493.5467
AppearanceWhite solid.
refractive index1.685
storage temp-20°C
Hazard Xn: Harmful;N: Dangerous for the environment;
Risk R21/22
Safety
Human poison by ingestion. Experimental poison by ingestion. Moderately toxic experimentally by skin contact. Human systemic effects by ingestion: weakness, respiratory changes, diarrhea, gastrointestinal disturbances, tremors, convulsions, coma, and death. Used as an insecticide. Flammable when exposed to heat or flame. To fight fire, use CO2, mist, spray, foam. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes
Xn,
N
Risk Statements 21/22-50/53
R20/21: Ryania (CAS NO. 15662-33-6) is harmful by inhalation and in contact with skin.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements 36/37-60-61
S36/37:Wear suitable protective clothing and gloves.
S60: Ryania (CAS NO. 15662-33-6) and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR UN 3077 9/PG 3
RTECS VM4025000
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orl-hmn LDLo:143 mg/kg:CNS,GIT,PUL
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34ZIAG Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,522. |
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orl-rat LD50:750 mg/kg
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WRPCA2 World Review of Pest Control. 9 (1970),119. |
3. |
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skn-rat LD50:750 mg/kg
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SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) 78-1,6 ,1978. |
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orl-mus LD50:650 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 93 (1948),407. |
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orl-dog LD50:150 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 93 (1948),407. |
6. |
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orl-rbt LD50:650 mg/kg
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GUCHAZ Guide to the Chemicals Used in Crop Protection 6 (1973),450. |
7. |
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orl-gpg LD50:2500 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 93 (1948),407. |
8. |
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orl-pgn LD50:2310 µg/kg
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ASTTA8 ASTM Special Technical Publication.(680)(1979),157. |
9. |
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orl-qal LD50:13,300 µg/kg
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ASTTA8 ASTM Special Technical Publication.(680)(1979),157. |
10. |
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orl-bwd LD50:1780 µg/kg
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