[1,1'-Biphenyl]-4,4'-diamine,2,2',5,5'-tetrachloro- cas no:15721-02-5
Synonyms: Benzidine,2,2',5,5'-tetrachloro- (6CI,8CI);2,2',5,5'-Tetrachlorobenzidine;3,3',6,6'-Tetrachlorobenzidine;4,4'-Diamino-2,2',5,5'-tetrachlorobiphenyl;Tetradine;
Name[1,1'-Biphenyl]-4,4'-diamine,2,2',5,5'-tetrachloro-
CAS15721-02-5
SynonymsBenzidine,2,2',5,5'-tetrachloro- (6CI,8CI);2,2',5,5'-Tetrachlorobenzidine;3,3',6,6'-Tetrachlorobenzidine;4,4'-Diamino-2,2',5,5'-tetrachlorobiphenyl;Tetradine;
EINECS(EC#)239-815-3
Molecular FormulaC12H8Cl4N2
Molecular Weight322.02
refractive index1.687
Safety
WGK Germany : 3
RTECS: DD1751000
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DD1751000
- CHEMICAL NAME :
- Benzidine, 2,2',5,5'-tetrachloro-
- CAS REGISTRY NUMBER :
- 15721-02-5
- BEILSTEIN REFERENCE NO. :
- 3364286
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C12-H8-Cl4-N2
- MOLECULAR WEIGHT :
- 322.02
- WISWESSER LINE NOTATION :
- ZR BG EG DR DZ CG FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 54 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- JMEJAS Jikeikai Medical Journal. (Jikei Univ. School of Medicine, 3-25-8
Nishi-shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1954-
Volume(issue)/page/year: 25,123,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 36 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Kidney, Ureter, Bladder - tumors
Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- JMEJAS Jikeikai Medical Journal. (Jikei Univ. School of Medicine, 3-25-8
Nishi-shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1954-
Volume(issue)/page/year: 25,123,1978
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 gm/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Skin and Appendages - tumors
- REFERENCE :
- IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 27,141,1982
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 gm/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
- REFERENCE :
- IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 27,141,1982
*** REVIEWS ***
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 27,141,1982
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 27,141,1982
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
