Vincamine cas no:1617-90-9
Synonyms: Vincapan;Pervincamine;Decincan;Eburnamenine-14-carboxylic acid,14,15-dihydro-14-hydroxy-,methyl ester,(3R,14a,16R)-;Vincamidol;Perval;Methyl vincaminate;Monorin;Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-;Minorin;Vinkametrin;Vinca-Ecobi;Anasclerol;Vincimax;Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3.alpha.,14.beta.,16.alpha.)-;Vinca-Minor;Equipur;Minorine;
NameVincamine
CAS1617-90-9
SynonymsVincapan;Pervincamine;Decincan;Eburnamenine-14-carboxylic acid,14,15-dihydro-14-hydroxy-,methyl ester,(3R,14a,16R)-;Vincamidol;Perval;Methyl vincaminate;Monorin;Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-;Minorin;Vinkametrin;Vinca-Ecobi;Anasclerol;Vincimax;Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3.alpha.,14.beta.,16.alpha.)-;Vinca-Minor;Equipur;Minorine;
EINECS(EC#)216-576-3
Molecular FormulaC21H26N2O3
Molecular Weight354.44
Appearancewhite to almost white fine crystalline powder
alpha42.8 º (C=1 IN PYRIDINE)
storage temp2-8°C
Hazard Xn:Harmful;
Risk R22
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. Used as a vasodilator.
Hazard Codes: 
Xn
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 36
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: YY8575000
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ipr-rat LD50:253 mg/kg
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ARZNAD Arzneimittel-Forschung. Drug Research. 32 (1982),601. |
| 2. |
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orl-mus LD50:1 g/kg
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ARZNAD Arzneimittel-Forschung. Drug Research. 10 (1960),811. |
| 3. |
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ipr-mus LD50:215 mg/kg
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EJMCA5 European Journal of Medicinal Chemistry. Chimie Therapeutique. 16 (1981),191. |
| 4. |
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ivn-mus LD50:47,740 µg/kg
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AGSOA6 Agressologie. Revue Internationale de Physio-Biologie et de Pharmacologie Appliquees aux Effets de l’Agression. 19 (1978),211. |
