1649-18-9|1-Butanone,1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-Products Supply

1-Butanone,1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]- cas no:1649-18-9

Synonyms: Butyrophenone,4'-fluoro-4-[4-(2-pyridyl)-1-piperazinyl]- (6CI,8CI);4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone;Fluoperidol;NSC 170976;R-1929;Stresnil;Suicalm;

Identification

Name1-Butanone,1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-
CAS1649-18-9
SynonymsButyrophenone,4'-fluoro-4-[4-(2-pyridyl)-1-piperazinyl]- (6CI,8CI);4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone;Fluoperidol;NSC 170976;R-1929;Stresnil;Suicalm;
EINECS(EC#)216-715-8
Molecular FormulaC₁₉H₂₂FN₃O
Molecular Weight327.4

Chemical Properties

AppearanceWhite or off-white crystalline
refractive index1.568
storage temp0-6°C

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Safety Information of Azaperone (CAS NO.1649-18-9):
Hazard Codes: Xn Harmful
Risk Statements: 22
22: Harmful if swallowed

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	oral	> 20mg/kg (20mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.
dog	LDLo	subcutaneous	> 40mg/kg (40mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.
guinea pig	LD50	oral	202mg/kg (202mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.
mouse	LD50	intraperitoneal	63mg/kg (63mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: REGIDITY	Farmaco, Edizione Scientifica. Vol. 35, Pg. 605, 1980.
mouse	LD50	intravenous	42mg/kg (42mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.
mouse	LD50	oral	385mg/kg (385mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.
mouse	LD50	subcutaneous	179mg/kg (179mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 185, 1972.
rat	LD50	intravenous	25mg/kg (25mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 185, 1972.
rat	LD50	oral	245mg/kg (245mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.
rat	LD50	subcutaneous	450mg/kg (450mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.

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1-Butanone,1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]- cas no:1649-18-9

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