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1,3-Benzodioxole-5-ethanamine,hydrochloride (1:1) cas no:1653-64-1

Synonyms: 1,3-Benzodioxole-5-ethanamine,hydrochloride (9CI); Phenethylamine, 3,4-(methylenedioxy)-, hydrochloride(6CI,7CI,8CI); 2-(3,4-Methylenedioxyphenyl)ethylamine chlorohydrate;2-(3,4-Methylenedioxyphenyl)ethylamine hydrochloride;3,4-(Methylenedioxy)phenylethylamine hydrochloride; 3,4-Methylenedioxy-b-phenylethylamine hydrochloride;3,4-Methylenedioxyphenethylamine hydrochloride;[2-(Benzodioxol-5-yl)ethyl]amine hydrochloride

Identification
Name1,3-Benzodioxole-5-ethanamine,hydrochloride (1:1)
CAS1653-64-1
Synonyms1,3-Benzodioxole-5-ethanamine,hydrochloride (9CI); Phenethylamine, 3,4-(methylenedioxy)-, hydrochloride(6CI,7CI,8CI); 2-(3,4-Methylenedioxyphenyl)ethylamine chlorohydrate;2-(3,4-Methylenedioxyphenyl)ethylamine hydrochloride;3,4-(Methylenedioxy)phenylethylamine hydrochloride; 3,4-Methylenedioxy-b-phenylethylamine hydrochloride;3,4-Methylenedioxyphenethylamine hydrochloride;[2-(Benzodioxol-5-yl)ethyl]amine hydrochloride
Molecular FormulaC9H11 N O2 . Cl H
Molecular Weight165.19
Chemical Properties
refractive index1.5620
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT, IRRITANT-HARMFUL, MOISTURE SENSITIVE
Safety Data

Hazard T+: Very toxic;Xi: Irritant;
Risk R26/27/28
Safety

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.Safety information of 3,4-Methylenedioxyphenethylamine hydrochloride (CAS NO.1653-64-1):
Hazard Codes  VeryT+,IrritantXi
Risk Statements 
26/27/28 Very Toxic by inhalation, in contact with skin and if swallowed
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements 
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39 Wear suitable protective clothing, gloves and eye/face protection
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  SH9710000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 28mg/kg (28mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
guinea pig LD50 intraperitoneal 245mg/kg (245mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
monkey LD50 intravenous 45mg/kg (45mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
mouse LD50 intraperitoneal 176mg/kg (176mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
rat LD50 intraperitoneal 55mg/kg (55mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.

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