1668-19-5|1-Propanamine,3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-Products Supply

1-Propanamine,3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl- cas no:1668-19-5

Synonyms: Dibenz[b,e]oxepin-D11(6H),g-propylamine, N,N-dimethyl-(7CI,8CI); Dibenz[b,e]oxepin, 1-propanamine deriv.;11-[3-(Dimethylamino)propylidene]-6H-dibenz[b,e]oxepin; Doxepin; Doxepine;N,N-Dimethyldibenz[b,e]oxepin-D11(6H),g-propylamine;NSC 108160

Identification

Name1-Propanamine,3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-
CAS1668-19-5
SynonymsDibenz[b,e]oxepin-D11(6H),g-propylamine, N,N-dimethyl-(7CI,8CI); Dibenz[b,e]oxepin, 1-propanamine deriv.;11-[3-(Dimethylamino)propylidene]-6H-dibenz[b,e]oxepin; Doxepin; Doxepine;N,N-Dimethyldibenz[b,e]oxepin-D11(6H),g-propylamine;NSC 108160
Molecular FormulaC19H21 N O
Molecular Weight279.41

Chemical Properties

Appearancewhite crystalline solid
storage tempStore at RT

Safety Data

Safety

Human poison by ingestion. Experimental poison by ingestion, intravenous, and intraperitoneal routes. A sedative and hypnotic used as an antianxiety agent. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	orl-hmn LDLo:60 mg/kg	CTOXAO Clinical Toxicology. 10 (1977),327.
2.	orl-rat LD50:147 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.
3.	ipr-rat LD50:182 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.
4.	ivn-rat LD50:16 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.
5.	orl-mus LD50:135 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.
6.	ipr-mus LD50:79 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.
7.	ivn-mus LD50:26 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.
8.	ivn-rbt LD50:11 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),863.

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1-Propanamine,3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl- cas no:1668-19-5

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