Propoxyphene Napsylate cas no:17140-78-2

Synonyms: naphthalene-2-sulphonic acid, compound with [S-(R*,S*)]-1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propionate (1:1); Dextropropoxyphene Napsilate

Directory

Identification
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Safety Data
Toxicity

Identification

NamePropoxyphene Napsylate
CAS17140-78-2
Synonymsnaphthalene-2-sulphonic acid, compound with [S-(R*,S*)]-1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propionate (1:1); Dextropropoxyphene Napsilate
EINECS(EC#)241-205-7
Molecular FormulaC22H29NO2?C10H8O3S
Molecular Weight547.712

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

Poison by ingestion. Human systemic effects by ingestion: somnolence, vascular changes. Experimental reproductive effects. When Doloxene (CAS NO.17140-78-2) is heated to decomposition ,it emits very toxic fumes of NO_x and SO_x. See also SULFONATES.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	129mg/kg (129mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) VASCULAR: OTHER CHANGES	Journal of Toxicology, Clinical Toxicology. Vol. 23, Pg. 347, 1985.
mouse	LD50	oral	915mg/kg (915mg/kg)		Toxicology and Applied Pharmacology. Vol. 19, Pg. 445, 1971.
rabbit	LDLo	oral	183mg/kg (183mg/kg)		Toxicology and Applied Pharmacology. Vol. 19, Pg. 445, 1971.
rat	LD50	oral	647mg/kg (647mg/kg)		Toxicology and Applied Pharmacology. Vol. 19, Pg. 445, 1971.

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