17455-13-9|18-Crown-6Products Supply - Chemical intermediates Network

18-Crown-6 cas no:17455-13-9

Synonyms: 1,4,7,10,13,16-Hexaoxacyclooctadecane; Crownwhitextl; 18-Crown-6-ether; (1,4,7,10,13,16-hexaoxacyclooctadecane)

Identification

Name18-Crown-6
CAS17455-13-9
Synonyms1,4,7,10,13,16-Hexaoxacyclooctadecane; Crownwhitextl; 18-Crown-6-ether; (1,4,7,10,13,16-hexaoxacyclooctadecane)
EINECS(EC#)241-473-5
Molecular FormulaC12H24O6
Molecular Weight264.32

Chemical Properties

AppearanceColorless crystals
refractive index1.4577 (50 C)
storage tempStore at 0-5°C
Sensitive Hygroscopic

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn:Harmful;
Risk R20/22;R36
Safety

Hazard Codes: Harmful Xn, Irritant Xi
Risk Statements: 22-36/37/38-36-20/22-20/21/22
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R36:Irritating to eyes.
R20/22:Harmful by inhalation and if swallowed.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36-39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S39:Wear eye / face protection.
RIDADR: 2811
WGK Germany: 3
RTECS: MP4500000
F: 10
HazardClass: 6.1(b)
PackingGroup of 18-Crown-6 (CAS NO.17455-13-9): III

HS Code 29329995

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	59mg/kg (59mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 92, 1988.
mouse	LD50	intraperitoneal	464mg/kg (464mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985.
mouse	LD50	intravenous	> 1gm/kg (1000mg/kg)		Russian Pharmacology and Toxicology Vol. 47, Pg. 167, 1984.
mouse	LD50	oral	540mg/kg (540mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 92, 1988.
rabbit	LD50	skin	3888mg/kg (3888mg/kg)	BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	National Technical Information Service. Vol. OTS0571014,
rat	LD50	intraperitoneal	830mg/kg (830mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985.
rat	LD50	intratracheal	56mg/kg (56mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: "FIBROSIS, FOCAL (PNEUMOCONIOSIS)" LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI	National Technical Information Service. Vol. OTS0536187,
rat	LD50	oral	525mg/kg (525mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 92, 1988.
rat	LDLo	skin	7gm/kg (7000mg/kg)		National Technical Information Service. Vol. OTS0540542,

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18-Crown-6 cas no:17455-13-9

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