Benzeneacetonitrile, a-[(1-methyl-2-phenylethyl)amino]- cas no:17590-01-1

NameBenzeneacetonitrile, a-[(1-methyl-2-phenylethyl)amino]-
CAS17590-01-1
SynonymsAcetonitrile,[(a-methylphenethyl)amino]phenyl-(8CI); Glycinonitrile, N-(a-methylphenethyl)-2-phenyl- (7CI); AN 1; AN 1 (pharmaceutical);Amfetaminil; Amphetaminil; Aponeuron; N-(b-Phenylisopropyl)-a-aminophenylacetonitrile; NSC 67172; dl-Amphetaminil; a-Phenyl-a-(1-phenylisopropyl)aminoacetonitrile;a-Phenyl-a-N-(1-phenylisopropyl)aminoacetonitrile;a-Phenyl-a-[N-(b-phenylisopropyl)amino]acetonitrile
EINECS(EC#)241-560-8
Molecular FormulaC17H18N2
Molecular Weight250.3383

AppearanceWhite to Off-White Solid
refractive index1.572

Safety

A poison by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic vapors of NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	491mg/kg (491mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 24, Pg. 823, 1977.
mouse	LD50	oral	182mg/kg (182mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 24, Pg. 823, 1977.
mouse	LD50	subcutaneous	58mg/kg (58mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 335, 1972.
rat	LD50	intraperitoneal	58800ug/kg (58.8mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 24, Pg. 823, 1977.
rat	LD50	oral	37600ug/kg (37.6mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 24, Pg. 823, 1977.
rat	LD50	subcutaneous	95100ug/kg (95.1mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 24, Pg. 823, 1977.