mouse
|
LD50
|
intraperitoneal
|
198mg/kg (198mg/kg)
|
behavioral: convulsions or effect on seizure threshold
behavioral: ataxia
gastrointestinal: ulceration or bleeding from stomach
|
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 655, 1973.
|
mouse
|
LD50
|
oral
|
400mg/kg (400mg/kg)
|
behavioral: convulsions or effect on seizure threshold
behavioral: ataxia
gastrointestinal: ulceration or bleeding from stomach
|
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 655, 1973.
|
mouse
|
LD50
|
subcutaneous
|
263mg/kg (263mg/kg)
|
behavioral: convulsions or effect on seizure threshold
behavioral: ataxia
gastrointestinal: ulceration or bleeding from stomach
|
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 655, 1973.
|
rat
|
LD50
|
intraperitoneal
|
148mg/kg (148mg/kg)
|
behavioral: convulsions or effect on seizure threshold
behavioral: ataxia
gastrointestinal: ulceration or bleeding from stomach
|
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 655, 1973.
|
rat
|
LD50
|
oral
|
335mg/kg (335mg/kg)
|
behavioral: convulsions or effect on seizure threshold
behavioral: ataxia
gastrointestinal: ulceration or bleeding from stomach
|
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 655, 1973.
|
rat
|
LD50
|
subcutaneous
|
325mg/kg (325mg/kg)
|
behavioral: convulsions or effect on seizure threshold
behavioral: ataxia
gastrointestinal: ulceration or bleeding from stomach
|
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 655, 1973.
|