Welcome to hiintermediates.com,intermediates trading platform
Home > products > D-threo-2-Pentulose,5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1®3)-O-2,6-dideoxy-b-D-lyxo-hexopyranosyl-(1®3)-2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-,(1S)- (9CI)

D-threo-2-Pentulose,5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1®3)-O-2,6-dideoxy-b-D-lyxo-hexopyranosyl-(1®3)-2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-,(1S)- (9CI) cas no:18378-89-7

Synonyms: Mithramycin(8CI);A 2371;Antibiotic LA 7017;Aureolic acid;Mithracin;Mithramycin A;Mitramycin;NSC 24559;PA 144;Plicamycin;Plicatomycin;[1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1?;3)-O-2,6-dideoxy-b-D-arabino-hexopyranosyl-(1?;3)-2,6-dideoxy-b-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose;

Identification
NameD-threo-2-Pentulose,5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1®3)-O-2,6-dideoxy-b-D-lyxo-hexopyranosyl-(1®3)-2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-,(1S)- (9CI)
CAS18378-89-7
SynonymsMithramycin(8CI);A 2371;Antibiotic LA 7017;Aureolic acid;Mithracin;Mithramycin A;Mitramycin;NSC 24559;PA 144;Plicamycin;Plicatomycin;[1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1?;3)-O-2,6-dideoxy-b-D-arabino-hexopyranosyl-(1?;3)-2,6-dideoxy-b-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose;
EINECS(EC#)232-455-8
Molecular FormulaC52H76 O24
Molecular Weight1085.14544
Chemical Properties
Appearanceyellow powder
refractive index1.639
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

A deadly poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: blood thrombocytopenia. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:
Xn: Harmful
T+: Very toxic
Risk Statements:
R22: Harmful if swallowed.
R26/27/28: Very toxic by inhalation, in contact with skin and if swallowed. 
Safety Statements:
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S38: In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S28: After contact with skin, wash immediately with plenty of soap-suds.
S22: Do not breathe dust.
RIDADR:3249
WGK Germany: 3
RTECS: PZ2800000
F: 10 Keep under argon.
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1.    

dnd-hmn:hla 1 mg/L

    CNREA8    Cancer Research. 45 (1985),2813.
2.    

msc-hmn:hla 40 µg/L

    CNREA8    Cancer Research. 45 (1985),2813.
3.    

orl-hmn TDLo:50 µg/kg/5D:BLD

    CORTBR    Clinical Orthopaedics and Related Research. 127 (1977),106.
4.    

ipr-rat LD50:2500 µg/kg

    ADTEAS    Advances in Teratology. 3 (1968),181.
5.    

ivn-rat LD50:1741 µg/kg

    NCICP*    Progress Report Submitted to the National Cancer Institute by Charles Pfizer and Company
6.    

orl-mus LD50:500 mg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 1 (1980),342.
7.    

ipr-mus LD50:1090 µg/kg

    ANTBAL    Antibiotiki. 21 (1976),258.
8.    

scu-mus LD50:2810 µg/kg

    ANTBAL    Antibiotiki. 21 (1976),258.
9.    

ivn-mus LD50:350 µg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1405.
10.    

ivn-dog LD50:250 µg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1405.
11.

supplier list

Jinan Haohua Industry Co., Ltd.
Tel:0086-531-58773055
Address: No.59 Gongye South RD
AFINE CHEMICALS LIMITED
Tel:86-571-85232161
Address: 6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China
Santa Cruz Biotechnology, Inc.
Tel:+1-(831)-457-3800
Address: 2145, Delaware Avenue, Santa Cruz, California 95060,
AppliChem mbH
Tel:+49 6151 93 57 0
Address: Ottoweg 4 D-64291 Darmstadt
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel:86-27-88660577
Address: 27th FL.shuian international masion Bldg.1,Heping Ave.wuhan city
Boc Sciences
Tel:1-631-5046093
Address: 45-16 Ramsey Road Shirley, NY 11967, USA
Onbio Inc.
Tel:+1-(905)707-1241 ++1.905.780.1700
Address: 26 Benson Avenue, Suite 101, Richmond Hill, Ontario, Canada L4C 4E6
Fermentek Ltd
Tel:972 2 5853953
Address: Yatziv 25, POB 47120, Jerusalem 97800 Israel

Home   |   About Us   |   Service   |   Links   |   Add to  Favorite

Copyright©2011 HiIntermediates ICP: B2-20090288 浙ICP备09045134号-49
Tel: +86-0571-89739792