18694-40-1|Pyrimidine,4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl-Products Supply

Pyrimidine,4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl- cas no:18694-40-1

Synonyms: Pyrimidine,4-methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methyl- (8CI); 1-(4-Methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole;1-(4-Methyl-6-methoxy-2-pyrimidinyl)-3-methyl-5-methoxypyrazole;2-(3-Methoxy-5-methylpyrazol-2-yl)-4-methoxy-6-methylpyrimidine;2-(3-Methyl-5-methoxy-1-pyrazolyl)-4-methoxy-6-methylpyrimidine; 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine;DA 398; Epirizole; Mebron; Mepirizole

Identification

NamePyrimidine,4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl-
CAS18694-40-1
SynonymsPyrimidine,4-methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methyl- (8CI); 1-(4-Methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole;1-(4-Methyl-6-methoxy-2-pyrimidinyl)-3-methyl-5-methoxypyrazole;2-(3-Methoxy-5-methylpyrazol-2-yl)-4-methoxy-6-methylpyrimidine;2-(3-Methyl-5-methoxy-1-pyrazolyl)-4-methoxy-6-methylpyrimidine; 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine;DA 398; Epirizole; Mebron; Mepirizole
EINECS(EC#)242-507-1
Molecular FormulaC11H14 N4 O2
Molecular Weight234.26

Chemical Properties

AppearanceYellow power
refractive index1.601
storage temp2-8°C

Safety Data

Hazard Xn:Harmful;
Risk R20/21/22;R36/37/38
Safety

Poison by subcutaneous, intravenous and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.
Safety Information of Mepirizol (CAS NO.18694-40-1):
Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
20: Harmful by inhalation
21: Harmful in contact with skin
22: Harmful if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 26-36
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	540mg/kg (540mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 1011, 1978.
mouse	LD50	intravenous	550mg/kg (550mg/kg)		Japan Medical Gazette. Vol. 7(9), Pg. 5, 1970.
mouse	LD50	oral	740mg/kg (740mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 1011, 1978.
mouse	LD50	subcutaneous	550mg/kg (550mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 494, 1977.
rat	LD50	intraperitoneal	214mg/kg (214mg/kg)		Japan Medical Gazette. Vol. 7(9), Pg. 5, 1970.
rat	LD50	intravenous	214mg/kg (214mg/kg)		"Modern Pharmaceuticals of Japan, V," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1975Vol. -, Pg. 87, 1975.
rat	LD50	oral	445mg/kg (445mg/kg)		Japan Medical Gazette. Vol. 7(9), Pg. 5, 1970.
rat	LD50	subcutaneous	208mg/kg (208mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 494, 1977.

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Pyrimidine,4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl- cas no:18694-40-1

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