1893-33-0|PipamperoneProducts Supply - Chemical intermediates Network

Pipamperone cas no:1893-33-0

Synonyms: [1,4'-Bipiperidine]-4'-carboxamide,1'-[3-(p-fluorobenzoyl)propyl]- (7CI,8CI); 1-(p-Fluorophenyl)-4-(4-piperidino-4-carbamoylpiperidino)-1-butanone;1'-[3-(p-Fluorobenzoyl)propyl][1,4'-bipiperidine]-4'-carboxamide;4'-Fluoro-4-[4-N-piperidino-4-carbamidopiperidino]butyrophenone;4'-Fluoro-4-{N-[4-(N-piperidino)-4-carbamido]piperidino}butyrophenone;Dipiperal; Dipiperon; Dipiperone; Floropipamide; McN-JR 3345; Pipamperone; R3345

Identification

NamePipamperone
CAS1893-33-0
Synonyms[1,4'-Bipiperidine]-4'-carboxamide,1'-[3-(p-fluorobenzoyl)propyl]- (7CI,8CI); 1-(p-Fluorophenyl)-4-(4-piperidino-4-carbamoylpiperidino)-1-butanone;1'-[3-(p-Fluorobenzoyl)propyl][1,4'-bipiperidine]-4'-carboxamide;4'-Fluoro-4-[4-N-piperidino-4-carbamidopiperidino]butyrophenone;4'-Fluoro-4-{N-[4-(N-piperidino)-4-carbamido]piperidino}butyrophenone;Dipiperal; Dipiperon; Dipiperone; Floropipamide; McN-JR 3345; Pipamperone; R3345
Molecular FormulaC21H30 F N3 O2
Molecular Weight135.13998

Chemical Properties

Appearancewhite powder
refractive index1.556

Safety Data

Hazard Xn
Risk 22
Safety

The Hazard Codes of Pipamperone (CAS NO.1893-33-0): Harmful Xn
Risk Statements: R22:Harmful if swallowed.
WGK Germany: 1
RTECS DW1060000
Poison by ingestion, subcutaneous, and intravenous routes. An experimental teratogen. When heated to decomposition it emits very toxic fumes of F⁻ and NO_x.

Toxicity

The toxicity of Pipamperone (CAS NO.1893-33-0):

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD₅₀	subcutaneous	> 10mg/kg (10mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 932, 1961.
dog	LD₅₀	subcutaneous	> 40mg/kg (40mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 932, 1961.
monkey	LD₅₀	subcutaneous	> 20mg/kg (20mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 932, 1961.
mouse	LD₅₀	intravenous	66mg/kg (66mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 188, 1972.
mouse	LD₅₀	oral	490mg/kg (490mg/kg)	BEHAVIORAL: TOXIC PSYCHOSIS	Pharmacology: International Journal of Experimental and Clinical Pharmacology. Vol. 15, Pg. 485, 1977.
mouse	LD₅₀	subcutaneous	160mg/kg (160mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 188, 1972.
rat	LD₅₀	intravenous	48mg/kg (48mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 188, 1972.
rat	LD₅₀	oral	160mg/kg (160mg/kg)		Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 611, 1961.
rat	LD₅₀	subcutaneous	160mg/kg (160mg/kg)		Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 611, 1961.

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Pipamperone cas no:1893-33-0

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