Pramipexole cas no:191217-81-9
Synonyms: 2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (6S)- (9CI);Mirapex;Pramipexole dihydrochloride monohydrate;2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, hydrochloride, hydrate (1:2:1), (6S)-;
NamePramipexole
CAS191217-81-9
Synonyms2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (6S)- (9CI);Mirapex;Pramipexole dihydrochloride monohydrate;2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, hydrochloride, hydrate (1:2:1), (6S)-;
Molecular FormulaC10H21Cl2N3OS
Molecular Weight302.26
Appearancewhite to off-white crystalline powder
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| child |
TDLo |
oral |
91ug/kg (0.091mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: NAUSEA OR VOMITING |
Journal of Toxicology, Clinical Toxicology. Vol. 37, Pg. 891, 1999. |
| mouse |
LDLo |
oral |
1700mg/kg (1700mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ATAXIA |
Journal of Toxicology, Clinical Toxicology. Vol. 37, Pg. 891, 1999. |
| rat |
LD50 |
oral |
> 800mg/kg (800mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ATAXIA |
Journal of Toxicology, Clinical Toxicology. Vol. 37, Pg. 891, 1999.
|
